Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AABA08_RS01685 Genome accession   NZ_AP028602
Coordinates   327959..328648 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PF2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 322959..333648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AABA08_RS01660 (TKY092604_03180) gpsB 323056..323397 (+) 342 WP_000146529.1 cell division regulator GpsB -
  AABA08_RS01670 (TKY092604_03190) - 323883..325040 (+) 1158 WP_000711371.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  AABA08_RS01675 (TKY092604_03200) mapZ 325053..326447 (+) 1395 WP_000039252.1 cell division site-positioning protein MapZ -
  AABA08_RS01680 (TKY092604_03210) gndA 326523..327947 (+) 1425 WP_000158768.1 NADP-dependent phosphogluconate dehydrogenase -
  AABA08_RS01685 (TKY092604_03220) covR 327959..328648 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  AABA08_RS01690 (TKY092604_03230) cbpC 328747..329769 (+) 1023 WP_000771083.1 choline-binding protein CbpC -
  AABA08_RS01695 (TKY092604_03240) cbpJ 329788..330786 (+) 999 WP_000771144.1 choline-binding protein CbpJ -
  AABA08_RS01700 - 330904..332136 (-) 1233 WP_000765691.1 MFS transporter -
  AABA08_RS01705 (TKY092604_03270) - 332179..333054 (-) 876 WP_010963214.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=105867 AABA08_RS01685 WP_000518018.1 327959..328648(+) (covR) [Streptococcus pneumoniae strain PF2]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=105867 AABA08_RS01685 WP_000518018.1 327959..328648(+) (covR) [Streptococcus pneumoniae strain PF2]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACACGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACTGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment