Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACFDBC_RS04660 Genome accession   NZ_CP170659
Coordinates   980326..980955 (+) Length   209 a.a.
NCBI ID   WP_020362447.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain CCARM 3A600     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 975326..985955
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDBC_RS04630 (ACFDBC_04630) - 975430..975966 (+) 537 WP_002447446.1 hypothetical protein -
  ACFDBC_RS04635 (ACFDBC_04635) - 976118..977104 (-) 987 WP_020363306.1 aromatic acid exporter family protein -
  ACFDBC_RS04640 (ACFDBC_04640) map 977278..978033 (+) 756 WP_002447444.1 type I methionyl aminopeptidase -
  ACFDBC_RS04645 (ACFDBC_04645) - 978191..978577 (+) 387 WP_002495657.1 hypothetical protein -
  ACFDBC_RS04650 (ACFDBC_04650) liaF 978592..979293 (+) 702 WP_002447442.1 cell wall-active antibiotics response protein LiaF -
  ACFDBC_RS04655 (ACFDBC_04655) vraS 979290..980336 (+) 1047 WP_002447441.1 sensor histidine kinase Regulator
  ACFDBC_RS04660 (ACFDBC_04660) vraR 980326..980955 (+) 630 WP_020362447.1 two-component system response regulator VraR Regulator
  ACFDBC_RS04665 (ACFDBC_04665) - 981012..982190 (-) 1179 WP_002447439.1 YihY/virulence factor BrkB family protein -
  ACFDBC_RS04670 (ACFDBC_04670) - 982596..982880 (-) 285 WP_002447438.1 YtxH domain-containing protein -
  ACFDBC_RS04675 (ACFDBC_04675) - 982888..983352 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  ACFDBC_RS04680 (ACFDBC_04680) - 983494..983709 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  ACFDBC_RS04685 (ACFDBC_04685) - 983711..984952 (+) 1242 Protein_919 aminopeptidase -
  ACFDBC_RS04690 (ACFDBC_04690) - 985033..985563 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23612.29 Da        Isoelectric Point: 4.8125

>NTDB_id=1058541 ACFDBC_RS04660 WP_020362447.1 980326..980955(+) (vraR) [Staphylococcus epidermidis strain CCARM 3A600]
MAIKILFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPKIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1058541 ACFDBC_RS04660 WP_020362447.1 980326..980955(+) (vraR) [Staphylococcus epidermidis strain CCARM 3A600]
GTGGCGATTAAAATTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAGGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTAAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.258

100

0.943
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment