Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACFXAB_RS07860 Genome accession   NZ_CP170650
Coordinates   1567696..1568340 (+) Length   214 a.a.
NCBI ID   WP_014418762.1    Uniprot ID   A0A2Z4EIP2
Organism   Bacillus velezensis strain JP5039     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1562696..1573340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFXAB_RS07835 (ACFXAB_07835) - 1563112..1563453 (-) 342 WP_014418765.1 hypothetical protein -
  ACFXAB_RS07840 (ACFXAB_07840) degQ 1563919..1564059 (+) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  ACFXAB_RS07845 (ACFXAB_07845) - 1564211..1565116 (+) 906 WP_014418764.1 polyprenyl synthetase family protein -
  ACFXAB_RS07850 (ACFXAB_07850) comX 1565116..1565286 (+) 171 WP_032863917.1 competence pheromone ComX -
  ACFXAB_RS07855 (ACFXAB_07855) comP 1565264..1567615 (+) 2352 WP_269800792.1 sensor histidine kinase Regulator
  ACFXAB_RS07860 (ACFXAB_07860) comA 1567696..1568340 (+) 645 WP_014418762.1 response regulator transcription factor Regulator
  ACFXAB_RS07865 (ACFXAB_07865) - 1568362..1568745 (+) 384 WP_014418761.1 hotdog fold thioesterase -
  ACFXAB_RS07870 (ACFXAB_07870) mnhG 1568785..1569159 (-) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  ACFXAB_RS07875 (ACFXAB_07875) - 1569143..1569427 (-) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  ACFXAB_RS07880 (ACFXAB_07880) - 1569427..1569903 (-) 477 WP_014418760.1 Na+/H+ antiporter subunit E -
  ACFXAB_RS07885 (ACFXAB_07885) - 1569909..1571390 (-) 1482 WP_032863920.1 Na+/H+ antiporter subunit D -
  ACFXAB_RS07890 (ACFXAB_07890) - 1571383..1571724 (-) 342 WP_014418758.1 Na(+)/H(+) antiporter subunit C -
  ACFXAB_RS07895 (ACFXAB_07895) - 1571724..1572155 (-) 432 WP_007613424.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24302.70 Da        Isoelectric Point: 4.9953

>NTDB_id=1058330 ACFXAB_RS07860 WP_014418762.1 1567696..1568340(+) (comA) [Bacillus velezensis strain JP5039]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTQRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1058330 ACFXAB_RS07860 WP_014418762.1 1567696..1568340(+) (comA) [Bacillus velezensis strain JP5039]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTTCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACACAGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCGATTGAATA
CAGCCTGACATCCATTTTTAACAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGTTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z4EIP2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

85.981

100

0.86

Multiple sequence alignment