Detailed information NTG1058322

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: ACFXAB_RS05880
• Genome accession: NZ_CP170650
• Coordinates: 1150142..1151305 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain JP5039
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1145142..1156305

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACFXAB_RS05860 (ACFXAB_05860)	-	1145558..1146754 (+)	1197	WP_014419014.1	glycosyltransferase	-
ACFXAB_RS05865 (ACFXAB_05865)	-	1146887..1147963 (+)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
ACFXAB_RS05870 (ACFXAB_05870)	-	1148053..1149267 (-)	1215	WP_014419013.1	LCP family protein	-
ACFXAB_RS05875 (ACFXAB_05875)	-	1149272..1149919 (-)	648	WP_007614107.1	YigZ family protein	-
ACFXAB_RS05880 (ACFXAB_05880)	degS	1150142..1151305 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
ACFXAB_RS05885 (ACFXAB_05885)	degU	1151382..1152071 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
ACFXAB_RS05890 (ACFXAB_05890)	-	1152169..1153017 (+)	849	WP_003151387.1	DegV family protein	-
ACFXAB_RS05895 (ACFXAB_05895)	comFA	1153125..1154510 (+)	1386	WP_014419012.1	DEAD/DEAH box helicase	Machinery gene
ACFXAB_RS05900 (ACFXAB_05900)	-	1154568..1154852 (+)	285	WP_014419011.1	late competence development ComFB family protein	-
ACFXAB_RS05905 (ACFXAB_05905)	comFC	1154858..1155547 (+)	690	WP_197535984.1	ComF family protein	Machinery gene
ACFXAB_RS05910 (ACFXAB_05910)	-	1155621..1156040 (+)	420	WP_014419009.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=1058322 ACFXAB_RS05880 WP_007407484.1 1150142..1151305(+) (degS) [Bacillus velezensis strain JP5039]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=1058322 ACFXAB_RS05880 WP_007407484.1 1150142..1151305(+) (degS) [Bacillus velezensis strain JP5039]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTAGGTCTTCAGGAAATCATTGAAC
GGTCAGAATCGTTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCTGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951