Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | ACFMSI_RS01485 | Genome accession | NZ_CP170579 |
| Coordinates | 335814..337163 (+) | Length | 449 a.a. |
| NCBI ID | WP_381543574.1 | Uniprot ID | - |
| Organism | Staphylococcus aureus strain JB2E56 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 303602..338337 | 335814..337163 | within | 0 |
Gene organization within MGE regions
Location: 303602..338337
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ACFMSI_RS01325 (ACFMSI_01325) | - | 303602..304414 (-) | 813 | WP_002504699.1 | abortive infection system antitoxin AbiGi family protein | - |
| ACFMSI_RS01330 (ACFMSI_01330) | - | 304605..306119 (+) | 1515 | WP_145426217.1 | class I SAM-dependent DNA methyltransferase | - |
| ACFMSI_RS01335 (ACFMSI_01335) | - | 306109..307389 (+) | 1281 | WP_381543572.1 | restriction endonuclease subunit S | - |
| ACFMSI_RS01340 (ACFMSI_01340) | - | 307373..310492 (+) | 3120 | WP_381543573.1 | type I restriction endonuclease subunit R | - |
| ACFMSI_RS01345 (ACFMSI_01345) | - | 310566..310787 (-) | 222 | WP_002504278.1 | hypothetical protein | - |
| ACFMSI_RS01350 (ACFMSI_01350) | - | 310802..311311 (-) | 510 | WP_145426223.1 | DUF1643 domain-containing protein | - |
| ACFMSI_RS01355 (ACFMSI_01355) | - | 311327..311638 (-) | 312 | WP_145426225.1 | DUF960 family protein | - |
| ACFMSI_RS01360 (ACFMSI_01360) | - | 311732..312070 (-) | 339 | WP_002449468.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| ACFMSI_RS01365 (ACFMSI_01365) | - | 312144..312491 (-) | 348 | Protein_272 | recombinase family protein | - |
| ACFMSI_RS01370 (ACFMSI_01370) | - | 312589..313119 (-) | 531 | WP_145426227.1 | hypothetical protein | - |
| ACFMSI_RS01375 (ACFMSI_01375) | - | 313558..313689 (-) | 132 | Protein_274 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| ACFMSI_RS01380 (ACFMSI_01380) | ccrC | 313797..315473 (-) | 1677 | WP_126116859.1 | cassette chromosome recombinase CcrC | - |
| ACFMSI_RS01385 (ACFMSI_01385) | - | 315698..317314 (-) | 1617 | WP_001015575.1 | DUF5906 domain-containing protein | - |
| ACFMSI_RS01390 (ACFMSI_01390) | - | 317314..317682 (-) | 369 | WP_001058155.1 | hypothetical protein | - |
| ACFMSI_RS01395 (ACFMSI_01395) | - | 317675..318784 (-) | 1110 | WP_000283873.1 | DNA polymerase | - |
| ACFMSI_RS01400 (ACFMSI_01400) | - | 318979..320967 (-) | 1989 | WP_001038847.1 | hypothetical protein | - |
| ACFMSI_RS01405 (ACFMSI_01405) | - | 321129..322058 (-) | 930 | WP_000750311.1 | YafY family protein | - |
| ACFMSI_RS01410 (ACFMSI_01410) | - | 322139..322567 (+) | 429 | WP_000671996.1 | VOC family protein | - |
| ACFMSI_RS01415 (ACFMSI_01415) | - | 322627..323301 (-) | 675 | Protein_282 | IS6 family transposase | - |
| ACFMSI_RS01420 (ACFMSI_01420) | - | 323342..323449 (-) | 108 | Protein_283 | beta-lactam sensor/signal transducer MecR1 | - |
| ACFMSI_RS01425 (ACFMSI_01425) | mecA | 323546..325555 (+) | 2010 | WP_063852638.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| ACFMSI_RS01430 (ACFMSI_01430) | - | 325601..326029 (-) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| ACFMSI_RS01435 (ACFMSI_01435) | - | 326126..326869 (-) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| ACFMSI_RS01440 (ACFMSI_01440) | - | 327786..328175 (-) | 390 | WP_020444595.1 | hydroxymethylglutaryl-CoA synthase | - |
| ACFMSI_RS01445 (ACFMSI_01445) | - | 328211..328885 (+) | 675 | Protein_288 | IS6 family transposase | - |
| ACFMSI_RS01450 (ACFMSI_01450) | - | 328986..329804 (-) | 819 | WP_002484875.1 | CPBP family intramembrane glutamic endopeptidase | - |
| ACFMSI_RS01455 (ACFMSI_01455) | - | 329841..330167 (-) | 327 | WP_012085243.1 | helix-turn-helix domain-containing protein | - |
| ACFMSI_RS01460 (ACFMSI_01460) | - | 331397..333322 (-) | 1926 | WP_070657144.1 | heavy metal translocating P-type ATPase | - |
| ACFMSI_RS01465 (ACFMSI_01465) | - | 333625..333951 (-) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| ACFMSI_RS01470 (ACFMSI_01470) | - | 334158..334517 (+) | 360 | WP_046465687.1 | hypothetical protein | - |
| ACFMSI_RS01475 (ACFMSI_01475) | - | 334629..334967 (-) | 339 | Protein_294 | recombinase family protein | - |
| ACFMSI_RS01480 (ACFMSI_01480) | - | 334976..335614 (+) | 639 | Protein_295 | hypothetical protein | - |
| ACFMSI_RS01485 (ACFMSI_01485) | ccrA | 335814..337163 (+) | 1350 | WP_381543574.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52442.19 Da Isoelectric Point: 9.9620
>NTDB_id=1058109 ACFMSI_RS01485 WP_381543574.1 335814..337163(+) (ccrA) [Staphylococcus aureus strain JB2E56]
MEEAIGYLRQSTLKQQSLSAQKQTIKALAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVSNGIKEKARQGKLITTHAPFGYHYH
NGTFTIDTVKAPTIKAVFNYYLQGYGYKKIAQYLEADNKFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEKAQVTRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKPDHSLRYYVCPQNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDVETKTTLNHEQLIEKLAQGKIDAETFREQTQSLHQQSKPISSISAYQIRKAFQ
NIIQQRFTLNMLYPYIDEINISKNKSLAGIYFKNEPLNIVKQTMKLSIV
MEEAIGYLRQSTLKQQSLSAQKQTIKALAEKHNIQHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVSNGIKEKARQGKLITTHAPFGYHYH
NGTFTIDTVKAPTIKAVFNYYLQGYGYKKIAQYLEADNKFINRKPYQVRNIILNPNYCGRVINQYGQYENMFPAIVSTTI
YEKAQVTRTQKQVKRKPSENQLKQKIKCPYCHSTLTNMTVRKPDHSLRYYVCPQNMNNARFVCEFKGINAQELETSVLAT
CQDFFQNQQLYSKINHTIQQRLKRQRDVETKTTLNHEQLIEKLAQGKIDAETFREQTQSLHQQSKPISSISAYQIRKAFQ
NIIQQRFTLNMLYPYIDEINISKNKSLAGIYFKNEPLNIVKQTMKLSIV
Nucleotide
Download Length: 1350 bp
>NTDB_id=1058109 ACFMSI_RS01485 WP_381543574.1 335814..337163(+) (ccrA) [Staphylococcus aureus strain JB2E56]
ATGGAAGAAGCCATTGGTTACTTACGTCAAAGTACACTCAAACAACAATCACTCTCAGCCCAGAAACAAACCATCAAGGC
ATTAGCCGAAAAGCATAATATTCAACACATTACCTTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGAAACGGTT
ACCAGCAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTGTGCCAAAAATATCATGTTCATATCTTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTTAAACTTAATATTTTCATCAGCTTGGCCGAATTAGAATCTGATAATATTGGCGAAC
AAGTAAGCAACGGGATAAAAGAAAAAGCGCGTCAGGGTAAATTGATAACTACACACGCCCCCTTTGGTTACCACTATCAT
AATGGTACTTTCACAATAGACACAGTAAAAGCACCAACAATAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATAATAAATTCATTAATCGCAAGCCCTATCAAGTGCGTAATATTATCCTTA
ATCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TATGAGAAAGCTCAAGTTACCCGAACTCAGAAACAAGTAAAACGTAAGCCGTCAGAAAATCAACTGAAACAAAAAATCAA
ATGTCCTTATTGTCATTCGACACTCACAAACATGACTGTCCGAAAACCAGATCATTCATTGCGTTACTATGTCTGTCCGC
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACCAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAACCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TGTAGAAACTAAAACTACACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACATCAACAATCAAAACCTATATCATCAATCAGTGCGTATCAAATTCGAAAAGCTTTCCAA
AACATCATTCAACAACGTTTCACACTAAACATGTTGTACCCCTATATTGATGAAATTAATATTTCTAAAAATAAAAGCCT
CGCTGGCATCTATTTCAAAAACGAACCACTGAATATTGTAAAGCAGACTATGAAATTATCAATTGTATAA
ATGGAAGAAGCCATTGGTTACTTACGTCAAAGTACACTCAAACAACAATCACTCTCAGCCCAGAAACAAACCATCAAGGC
ATTAGCCGAAAAGCATAATATTCAACACATTACCTTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGAAACGGTT
ACCAGCAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTGTGCCAAAAATATCATGTTCATATCTTAAGTGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTTAAACTTAATATTTTCATCAGCTTGGCCGAATTAGAATCTGATAATATTGGCGAAC
AAGTAAGCAACGGGATAAAAGAAAAAGCGCGTCAGGGTAAATTGATAACTACACACGCCCCCTTTGGTTACCACTATCAT
AATGGTACTTTCACAATAGACACAGTAAAAGCACCAACAATAAAAGCTGTGTTCAATTATTACCTTCAAGGTTATGGTTA
TAAAAAAATTGCGCAATACTTAGAAGCTGATAATAAATTCATTAATCGCAAGCCCTATCAAGTGCGTAATATTATCCTTA
ATCCTAATTACTGTGGCCGTGTTATCAATCAATACGGACAATATGAAAACATGTTCCCAGCTATTGTCAGTACAACGATA
TATGAGAAAGCTCAAGTTACCCGAACTCAGAAACAAGTAAAACGTAAGCCGTCAGAAAATCAACTGAAACAAAAAATCAA
ATGTCCTTATTGTCATTCGACACTCACAAACATGACTGTCCGAAAACCAGATCATTCATTGCGTTACTATGTCTGTCCGC
AAAATATGAATAACGCTCGCTTTGTTTGTGAATTTAAAGGAATCAACGCACAAGAATTAGAAACCAGTGTTTTAGCGACT
TGTCAGGACTTCTTTCAAAATCAACAGCTCTATTCAAAAATAAACCATACTATTCAACAACGACTCAAAAGACAAAGAGA
TGTAGAAACTAAAACTACACTCAATCACGAGCAGCTGATAGAAAAATTAGCCCAAGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACATCAACAATCAAAACCTATATCATCAATCAGTGCGTATCAAATTCGAAAAGCTTTCCAA
AACATCATTCAACAACGTTTCACACTAAACATGTTGTACCCCTATATTGATGAAATTAATATTTCTAAAAATAAAAGCCT
CGCTGGCATCTATTTCAAAAACGAACCACTGAATATTGTAAAGCAGACTATGAAATTATCAATTGTATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
94.209 |
100 |
0.942 |
| ccrA | Staphylococcus aureus N315 |
73.719 |
100 |
0.737 |