Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AAA982_RS02005 Genome accession   NZ_AP028601
Coordinates   379200..379889 (+) Length   229 a.a.
NCBI ID   WP_338168323.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PF1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 374200..384889
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAA982_RS01980 (TKY113292_03820) gpsB 374310..374639 (+) 330 WP_000146522.1 cell division regulator GpsB -
  AAA982_RS01990 (TKY113292_03830) - 375125..376282 (+) 1158 WP_000711375.1 class I SAM-dependent RNA methyltransferase -
  AAA982_RS01995 (TKY113292_03840) mapZ 376294..377688 (+) 1395 WP_000039304.1 mid-cell-anchored protein MapZ -
  AAA982_RS02000 (TKY113292_03850) gndA 377764..379188 (+) 1425 WP_000158795.1 NADP-dependent phosphogluconate dehydrogenase -
  AAA982_RS02005 (TKY113292_03860) covR 379200..379889 (+) 690 WP_338168323.1 response regulator transcription factor Regulator
  AAA982_RS02010 (TKY113292_03870) cbpC 379987..381009 (+) 1023 WP_317649268.1 choline-binding protein CbpC -
  AAA982_RS02015 (TKY113292_03880) cbpC 381028..382047 (+) 1020 WP_338168324.1 choline-binding protein CbpC -
  AAA982_RS02020 (TKY113292_03890) - 382165..383397 (-) 1233 WP_115346848.1 MFS transporter -
  AAA982_RS02025 (TKY113292_03900) - 383440..383940 (-) 501 WP_142760857.1 lanthionine synthetase LanC family protein -
  AAA982_RS02030 (TKY113292_03910) - 383927..384216 (-) 290 Protein_397 lantibiotic-modifying protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26952.25 Da        Isoelectric Point: 6.6546

>NTDB_id=105792 AAA982_RS02005 WP_338168323.1 379200..379889(+) (covR) [Streptococcus pneumoniae strain PF1]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMESKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=105792 AAA982_RS02005 WP_338168323.1 379200..379889(+) (covR) [Streptococcus pneumoniae strain PF1]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGAAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment