Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACFIOI_RS06245 Genome accession   NZ_CP170432
Coordinates   1196745..1197431 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain t1476     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1191745..1202431
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOI_RS06210 yqeH 1192272..1193372 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  ACFIOI_RS06215 aroE 1193386..1194192 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  ACFIOI_RS06220 yhbY 1194196..1194486 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  ACFIOI_RS06225 nadD 1194489..1195058 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACFIOI_RS06230 yqeK 1195048..1195632 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACFIOI_RS06235 rsfS 1195633..1195986 (+) 354 WP_001088022.1 ribosome silencing factor -
  ACFIOI_RS06240 - 1195989..1196705 (+) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  ACFIOI_RS06245 comEA 1196745..1197431 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  ACFIOI_RS06250 - 1197523..1197984 (+) 462 WP_000439693.1 ComE operon protein 2 -
  ACFIOI_RS06255 comEC 1197989..1200190 (+) 2202 WP_001805151.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACFIOI_RS06260 holA 1200247..1201221 (+) 975 WP_001282562.1 DNA polymerase III subunit delta -
  ACFIOI_RS06265 rpsT 1201266..1201517 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=1057271 ACFIOI_RS06245 WP_001792568.1 1196745..1197431(+) (comEA) [Staphylococcus aureus strain t1476]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1057271 ACFIOI_RS06245 WP_001792568.1 1196745..1197431(+) (comEA) [Staphylococcus aureus strain t1476]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969

Multiple sequence alignment