Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACFIOD_RS11070 Genome accession   NZ_CP170429
Coordinates   2203839..2204408 (-) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain t1531     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2198839..2209408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOD_RS11030 - 2199313..2199921 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  ACFIOD_RS11035 rplL 2200096..2200464 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACFIOD_RS11040 rplJ 2200507..2201007 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACFIOD_RS11045 rplA 2201279..2201971 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACFIOD_RS11050 rplK 2202179..2202601 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACFIOD_RS11055 nusG 2202782..2203330 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACFIOD_RS11060 secE 2203343..2203525 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACFIOD_RS11065 rpmG 2203581..2203724 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACFIOD_RS11070 sigH 2203839..2204408 (-) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACFIOD_RS11075 - 2204489..2205013 (-) 525 WP_000664737.1 NYN domain-containing protein -
  ACFIOD_RS11080 rlmB 2205013..2205759 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACFIOD_RS11085 - 2205767..2206171 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  ACFIOD_RS11090 cysS 2206164..2207564 (-) 1401 WP_000631969.1 cysteine--tRNA ligase -
  ACFIOD_RS11095 cysE 2207548..2208195 (-) 648 WP_103150789.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=1057249 ACFIOD_RS11070 WP_000872882.1 2203839..2204408(-) (sigH) [Staphylococcus aureus strain t1531]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1057249 ACFIOD_RS11070 WP_000872882.1 2203839..2204408(-) (sigH) [Staphylococcus aureus strain t1531]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment