Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACFIOD_RS06035 Genome accession   NZ_CP170429
Coordinates   1152573..1153259 (+) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain t1531     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1147573..1158259
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOD_RS06000 yqeH 1148100..1149200 (+) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -
  ACFIOD_RS06005 aroE 1149214..1150020 (+) 807 WP_000666757.1 shikimate dehydrogenase -
  ACFIOD_RS06010 yhbY 1150024..1150314 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  ACFIOD_RS06015 nadD 1150317..1150886 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACFIOD_RS06020 yqeK 1150876..1151460 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACFIOD_RS06025 rsfS 1151461..1151814 (+) 354 WP_001088020.1 ribosome silencing factor -
  ACFIOD_RS06030 - 1151817..1152533 (+) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  ACFIOD_RS06035 comEA 1152573..1153259 (+) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  ACFIOD_RS06040 - 1153351..1153812 (+) 462 WP_000439693.1 ComE operon protein 2 -
  ACFIOD_RS06045 comEC 1153817..1156018 (+) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACFIOD_RS06050 holA 1156075..1157049 (+) 975 WP_001282563.1 DNA polymerase III subunit delta -
  ACFIOD_RS06055 rpsT 1157094..1157345 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=1057229 ACFIOD_RS06035 WP_001802022.1 1152573..1153259(+) (comEA) [Staphylococcus aureus strain t1531]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1057229 ACFIOD_RS06035 WP_001802022.1 1152573..1153259(+) (comEA) [Staphylococcus aureus strain t1531]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974

Multiple sequence alignment