Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACFIOC_RS08075 Genome accession   NZ_CP170419
Coordinates   1647683..1648369 (-) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain t062     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1642683..1653369
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOC_RS08055 rpsT 1643597..1643848 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  ACFIOC_RS08060 holA 1643893..1644867 (-) 975 WP_001282563.1 DNA polymerase III subunit delta -
  ACFIOC_RS08065 comEC 1644924..1647125 (-) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACFIOC_RS08070 - 1647130..1647591 (-) 462 WP_000439693.1 ComE operon protein 2 -
  ACFIOC_RS08075 comEA 1647683..1648369 (-) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  ACFIOC_RS08080 - 1648409..1649125 (-) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  ACFIOC_RS08085 rsfS 1649128..1649481 (-) 354 WP_001088020.1 ribosome silencing factor -
  ACFIOC_RS08090 yqeK 1649482..1650066 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACFIOC_RS08095 nadD 1650056..1650625 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACFIOC_RS08100 yhbY 1650628..1650918 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  ACFIOC_RS08105 aroE 1650922..1651728 (-) 807 WP_000666757.1 shikimate dehydrogenase -
  ACFIOC_RS08110 yqeH 1651742..1652842 (-) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=1057066 ACFIOC_RS08075 WP_001802022.1 1647683..1648369(-) (comEA) [Staphylococcus aureus strain t062]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1057066 ACFIOC_RS08075 WP_001802022.1 1647683..1648369(-) (comEA) [Staphylococcus aureus strain t062]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974

Multiple sequence alignment