Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACFIOC_RS02470 Genome accession   NZ_CP170419
Coordinates   525784..526353 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain t062     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 520784..531353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOC_RS02445 cysE 521997..522644 (+) 648 WP_103150789.1 serine O-acetyltransferase -
  ACFIOC_RS02450 cysS 522628..524028 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  ACFIOC_RS02455 - 524021..524425 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  ACFIOC_RS02460 rlmB 524433..525179 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACFIOC_RS02465 - 525179..525703 (+) 525 WP_000664737.1 NYN domain-containing protein -
  ACFIOC_RS02470 sigH 525784..526353 (+) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACFIOC_RS02475 rpmG 526468..526611 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACFIOC_RS02480 secE 526667..526849 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACFIOC_RS02485 nusG 526862..527410 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACFIOC_RS02490 rplK 527591..528013 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACFIOC_RS02495 rplA 528221..528913 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACFIOC_RS02500 rplJ 529185..529685 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACFIOC_RS02505 rplL 529728..530096 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACFIOC_RS02510 - 530271..530879 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=1057045 ACFIOC_RS02470 WP_000872882.1 525784..526353(+) (sigH) [Staphylococcus aureus strain t062]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1057045 ACFIOC_RS02470 WP_000872882.1 525784..526353(+) (sigH) [Staphylococcus aureus strain t062]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment