Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACFIOE_RS07540 Genome accession   NZ_CP170411
Coordinates   1579037..1579723 (-) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain t002     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1574037..1584723
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOE_RS07520 rpsT 1574951..1575202 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  ACFIOE_RS07525 holA 1575247..1576221 (-) 975 WP_001282563.1 DNA polymerase III subunit delta -
  ACFIOE_RS07530 comEC 1576278..1578479 (-) 2202 WP_410538064.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACFIOE_RS07535 - 1578484..1578945 (-) 462 WP_000439693.1 ComE operon protein 2 -
  ACFIOE_RS07540 comEA 1579037..1579723 (-) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  ACFIOE_RS07545 - 1579763..1580479 (-) 717 WP_000084830.1 class I SAM-dependent DNA methyltransferase -
  ACFIOE_RS07550 rsfS 1580482..1580835 (-) 354 WP_001088020.1 ribosome silencing factor -
  ACFIOE_RS07555 yqeK 1580836..1581420 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACFIOE_RS07560 nadD 1581410..1581979 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACFIOE_RS07565 yhbY 1581982..1582272 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  ACFIOE_RS07570 aroE 1582276..1583082 (-) 807 WP_000666757.1 shikimate dehydrogenase -
  ACFIOE_RS07575 yqeH 1583096..1584196 (-) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=1056940 ACFIOE_RS07540 WP_001802022.1 1579037..1579723(-) (comEA) [Staphylococcus aureus strain t002]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1056940 ACFIOE_RS07540 WP_001802022.1 1579037..1579723(-) (comEA) [Staphylococcus aureus strain t002]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974

Multiple sequence alignment