Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   ACFIOO_RS07335 Genome accession   NZ_CP170406
Coordinates   1542130..1543104 (-) Length   324 a.a.
NCBI ID   WP_054191886.1    Uniprot ID   -
Organism   Staphylococcus aureus strain t21635     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1537130..1548104
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOO_RS07295 gcvT 1537631..1538722 (-) 1092 WP_054190022.1 glycine cleavage system aminomethyltransferase GcvT -
  ACFIOO_RS07300 - 1538881..1539405 (-) 525 WP_054190023.1 shikimate kinase -
  ACFIOO_RS07305 - 1539395..1539541 (-) 147 WP_001789879.1 hypothetical protein -
  ACFIOO_RS07310 comGF 1539638..1540135 (-) 498 WP_077446653.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACFIOO_RS07315 comGE 1540053..1540352 (-) 300 WP_054190024.1 hypothetical protein Machinery gene
  ACFIOO_RS07320 comGD 1540339..1540785 (-) 447 WP_077446655.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACFIOO_RS07325 comGC 1540763..1541074 (-) 312 WP_054190026.1 competence type IV pilus major pilin ComGC Machinery gene
  ACFIOO_RS07330 comGB 1541088..1542158 (-) 1071 WP_054190027.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACFIOO_RS07335 comGA 1542130..1543104 (-) 975 WP_054191886.1 competence type IV pilus ATPase ComGA Machinery gene
  ACFIOO_RS07340 - 1543156..1543779 (-) 624 WP_054190028.1 MBL fold metallo-hydrolase -
  ACFIOO_RS07345 - 1543776..1544105 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  ACFIOO_RS07350 - 1544105..1545091 (-) 987 WP_000161315.1 ROK family glucokinase -
  ACFIOO_RS07355 - 1545088..1545291 (-) 204 WP_000087561.1 YqgQ family protein -
  ACFIOO_RS07360 - 1545272..1546735 (-) 1464 WP_054190029.1 rhomboid family protein -
  ACFIOO_RS07365 - 1546747..1547286 (-) 540 WP_077519960.1 5-formyltetrahydrofolate cyclo-ligase -
  ACFIOO_RS07370 rpmG 1547495..1547644 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36912.97 Da        Isoelectric Point: 8.6529

>NTDB_id=1056853 ACFIOO_RS07335 WP_054191886.1 1542130..1543104(-) (comGA) [Staphylococcus aureus strain t21635]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLIYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHDHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=1056853 ACFIOO_RS07335 WP_054191886.1 1542130..1543104(-) (comGA) [Staphylococcus aureus strain t21635]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAATTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAAAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGTCCAACTGGTTCAGGTAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAGGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAGGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATGATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.383

100

0.994
  comGA Staphylococcus aureus N315

99.383

100

0.994

Multiple sequence alignment