Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACFIOQ_RS06110 Genome accession   NZ_CP170404
Coordinates   1175120..1175806 (+) Length   228 a.a.
NCBI ID   WP_072357801.1    Uniprot ID   A0A6B5EZE0
Organism   Staphylococcus aureus strain t7960     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1170120..1180806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOQ_RS06075 yqeH 1170647..1171747 (+) 1101 WP_410532243.1 ribosome biogenesis GTPase YqeH -
  ACFIOQ_RS06080 aroE 1171761..1172567 (+) 807 WP_000666752.1 shikimate dehydrogenase -
  ACFIOQ_RS06085 yhbY 1172571..1172861 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  ACFIOQ_RS06090 nadD 1172864..1173433 (+) 570 WP_000725160.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACFIOQ_RS06095 yqeK 1173423..1174007 (+) 585 WP_001019325.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACFIOQ_RS06100 rsfS 1174008..1174361 (+) 354 WP_001088020.1 ribosome silencing factor -
  ACFIOQ_RS06105 - 1174364..1175080 (+) 717 WP_000084828.1 class I SAM-dependent DNA methyltransferase -
  ACFIOQ_RS06110 comEA 1175120..1175806 (+) 687 WP_072357801.1 ComEA family DNA-binding protein Machinery gene
  ACFIOQ_RS06115 - 1175898..1176359 (+) 462 WP_000439693.1 ComE operon protein 2 -
  ACFIOQ_RS06120 comEC 1176364..1178565 (+) 2202 WP_042908045.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACFIOQ_RS06125 holA 1178622..1179596 (+) 975 WP_001282559.1 DNA polymerase III subunit delta -
  ACFIOQ_RS06130 rpsT 1179641..1179892 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25759.47 Da        Isoelectric Point: 9.6753

>NTDB_id=1056807 ACFIOQ_RS06110 WP_072357801.1 1175120..1175806(+) (comEA) [Staphylococcus aureus strain t7960]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLSDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNINNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1056807 ACFIOQ_RS06110 WP_072357801.1 1175120..1175806(+) (comEA) [Staphylococcus aureus strain t7960]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTATCAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCACGTAAAAAAT
GGAAACATAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6B5EZE0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

97.797

99.561

0.974
  comEA Staphylococcus aureus N315

97.797

99.561

0.974

Multiple sequence alignment