Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACFIOB_RS07565 Genome accession   NZ_CP170401
Coordinates   1585700..1586386 (-) Length   228 a.a.
NCBI ID   WP_072468915.1    Uniprot ID   A0A5F0HFN7
Organism   Staphylococcus aureus strain t10543     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1580700..1591386
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOB_RS07545 rpsT 1581614..1581865 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  ACFIOB_RS07550 holA 1581910..1582884 (-) 975 WP_001282573.1 DNA polymerase III subunit delta -
  ACFIOB_RS07555 comEC 1582941..1585142 (-) 2202 WP_410539845.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACFIOB_RS07560 - 1585147..1585608 (-) 462 WP_000439693.1 ComE operon protein 2 -
  ACFIOB_RS07565 comEA 1585700..1586386 (-) 687 WP_072468915.1 ComEA family DNA-binding protein Machinery gene
  ACFIOB_RS07570 - 1586426..1587142 (-) 717 WP_000084840.1 class I SAM-dependent DNA methyltransferase -
  ACFIOB_RS07575 rsfS 1587145..1587498 (-) 354 WP_001088020.1 ribosome silencing factor -
  ACFIOB_RS07580 yqeK 1587499..1588083 (-) 585 WP_001017837.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACFIOB_RS07585 nadD 1588073..1588642 (-) 570 WP_000725165.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACFIOB_RS07590 yhbY 1588645..1588935 (-) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  ACFIOB_RS07595 aroE 1588939..1589745 (-) 807 WP_000666766.1 shikimate dehydrogenase -
  ACFIOB_RS07600 yqeH 1589759..1590859 (-) 1101 WP_001280146.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25812.41 Da        Isoelectric Point: 9.3305

>NTDB_id=1056774 ACFIOB_RS07565 WP_072468915.1 1585700..1586386(-) (comEA) [Staphylococcus aureus strain t10543]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQAKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGENSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1056774 ACFIOB_RS07565 WP_072468915.1 1585700..1586386(-) (comEA) [Staphylococcus aureus strain t10543]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGCCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACACCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGAAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HFN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment