Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   ACFION_RS05955 Genome accession   NZ_CP170399
Coordinates   1162051..1162737 (+) Length   228 a.a.
NCBI ID   WP_001793467.1    Uniprot ID   A0A641AAY3
Organism   Staphylococcus aureus strain t127     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1157051..1167737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFION_RS05920 yqeH 1157578..1158678 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  ACFION_RS05925 aroE 1158692..1159498 (+) 807 WP_000666748.1 shikimate dehydrogenase -
  ACFION_RS05930 yhbY 1159502..1159792 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  ACFION_RS05935 nadD 1159795..1160364 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  ACFION_RS05940 yqeK 1160354..1160938 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  ACFION_RS05945 rsfS 1160939..1161292 (+) 354 WP_001088022.1 ribosome silencing factor -
  ACFION_RS05950 - 1161295..1162011 (+) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  ACFION_RS05955 comEA 1162051..1162737 (+) 687 WP_001793467.1 ComEA family DNA-binding protein Machinery gene
  ACFION_RS05960 - 1162829..1163290 (+) 462 WP_000439693.1 ComE operon protein 2 -
  ACFION_RS05965 comEC 1163295..1165496 (+) 2202 WP_001566670.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACFION_RS05970 holA 1165553..1166527 (+) 975 WP_001282568.1 DNA polymerase III subunit delta -
  ACFION_RS05975 rpsT 1166572..1166823 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25786.50 Da        Isoelectric Point: 9.6753

>NTDB_id=1056723 ACFION_RS05955 WP_001793467.1 1162051..1162737(+) (comEA) [Staphylococcus aureus strain t127]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDNALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1056723 ACFION_RS05955 WP_001793467.1 1162051..1162737(+) (comEA) [Staphylococcus aureus strain t127]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATAATG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641AAY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

100

100

1
  comEA Staphylococcus aureus N315

97.368

100

0.974

Multiple sequence alignment