Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACFIOP_RS02600 Genome accession   NZ_CP170392
Coordinates   556630..557199 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain t442     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 551630..562199
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFIOP_RS02575 cysE 552843..553490 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  ACFIOP_RS02580 cysS 553474..554874 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  ACFIOP_RS02585 - 554867..555271 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  ACFIOP_RS02590 rlmB 555279..556025 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACFIOP_RS02595 - 556025..556549 (+) 525 WP_000664737.1 NYN domain-containing protein -
  ACFIOP_RS02600 sigH 556630..557199 (+) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACFIOP_RS02605 rpmG 557314..557457 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACFIOP_RS02610 secE 557513..557695 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACFIOP_RS02615 nusG 557708..558256 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACFIOP_RS02620 rplK 558437..558859 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACFIOP_RS02625 rplA 559067..559759 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACFIOP_RS02630 rplJ 560031..560531 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACFIOP_RS02635 rplL 560574..560942 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACFIOP_RS02640 - 561117..561725 (+) 609 WP_103242871.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=1056626 ACFIOP_RS02600 WP_000872882.1 556630..557199(+) (sigH) [Staphylococcus aureus strain t442]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1056626 ACFIOP_RS02600 WP_000872882.1 556630..557199(+) (sigH) [Staphylococcus aureus strain t442]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment