Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACFDBD_RS04565 Genome accession   NZ_CP170249
Coordinates   985704..986333 (+) Length   209 a.a.
NCBI ID   WP_002447440.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain HS01     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 980704..991333
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDBD_RS04535 (ACFDBD_04530) - 980808..981344 (+) 537 WP_002447446.1 hypothetical protein -
  ACFDBD_RS04540 (ACFDBD_04535) - 981496..982482 (-) 987 WP_002447445.1 aromatic acid exporter family protein -
  ACFDBD_RS04545 (ACFDBD_04540) map 982656..983411 (+) 756 WP_002447444.1 type I methionyl aminopeptidase -
  ACFDBD_RS04550 (ACFDBD_04545) - 983569..983955 (+) 387 WP_002495657.1 hypothetical protein -
  ACFDBD_RS04555 (ACFDBD_04550) liaF 983970..984671 (+) 702 WP_002447442.1 cell wall-active antibiotics response protein LiaF -
  ACFDBD_RS04560 (ACFDBD_04555) vraS 984668..985714 (+) 1047 WP_002447441.1 sensor histidine kinase Regulator
  ACFDBD_RS04565 (ACFDBD_04560) vraR 985704..986333 (+) 630 WP_002447440.1 two-component system response regulator VraR Regulator
  ACFDBD_RS04570 (ACFDBD_04565) - 986390..987568 (-) 1179 WP_002447439.1 YihY/virulence factor BrkB family protein -
  ACFDBD_RS04575 (ACFDBD_04570) - 987974..988258 (-) 285 WP_002447438.1 YtxH domain-containing protein -
  ACFDBD_RS04580 (ACFDBD_04575) - 988266..988730 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  ACFDBD_RS04585 (ACFDBD_04580) - 988872..989087 (+) 216 WP_381407032.1 DUF1128 domain-containing protein -
  ACFDBD_RS04590 (ACFDBD_04585) - 989089..990330 (+) 1242 WP_020361889.1 aminopeptidase -
  ACFDBD_RS04595 (ACFDBD_04590) - 990411..990941 (+) 531 WP_002447436.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23612.25 Da        Isoelectric Point: 4.7218

>NTDB_id=1055999 ACFDBD_RS04565 WP_002447440.1 985704..986333(+) (vraR) [Staphylococcus epidermidis strain HS01]
MAIKILFVDDHEMVRIGISSYLSTQEDIEVVGEGASGKEAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1055999 ACFDBD_RS04565 WP_002447440.1 985704..986333(+) (vraR) [Staphylococcus epidermidis strain HS01]
GTGGCGATTAAAATTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAAGCTATCTTTCAACACAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAGGAAGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCTACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAAGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAACCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTAACAGAAAGAGAAATGGAGATCTTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
GAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATCTATGCGTTTCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.737

100

0.947
  degU Bacillus subtilis subsp. subtilis str. 168

35.268

100

0.378

Multiple sequence alignment