Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACFDHW_RS12605 Genome accession   NZ_CP170222
Coordinates   2513143..2513772 (-) Length   209 a.a.
NCBI ID   WP_039644795.1    Uniprot ID   A0A0A8HRY9
Organism   Staphylococcus hyicus strain SC382     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2508143..2518772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFDHW_RS12570 (ACFDHW_12595) - 2508218..2508736 (-) 519 WP_039644807.1 acyl-CoA thioesterase -
  ACFDHW_RS12575 (ACFDHW_12600) - 2508750..2509985 (-) 1236 WP_039644805.1 aminopeptidase -
  ACFDHW_RS12580 (ACFDHW_12605) - 2510002..2510211 (-) 210 WP_039644804.1 DUF1128 family protein -
  ACFDHW_RS12585 (ACFDHW_12610) - 2510344..2510802 (+) 459 WP_039644802.1 low molecular weight protein-tyrosine-phosphatase -
  ACFDHW_RS12590 (ACFDHW_12615) - 2510809..2511084 (+) 276 WP_039644801.1 hypothetical protein -
  ACFDHW_RS12595 (ACFDHW_12620) - 2511204..2512475 (+) 1272 WP_107633458.1 YihY/virulence factor BrkB family protein -
  ACFDHW_RS12600 (ACFDHW_12625) - 2512510..2513079 (+) 570 WP_039644796.1 carbonic anhydrase -
  ACFDHW_RS12605 (ACFDHW_12630) vraR 2513143..2513772 (-) 630 WP_039644795.1 response regulator transcription factor Regulator
  ACFDHW_RS12610 (ACFDHW_12635) vraS 2513762..2514805 (-) 1044 WP_039644794.1 sensor histidine kinase Regulator
  ACFDHW_RS12615 (ACFDHW_12640) liaF 2514802..2515503 (-) 702 WP_107633459.1 cell wall-active antibiotics response protein LiaF -
  ACFDHW_RS12620 (ACFDHW_12645) - 2515516..2515902 (-) 387 WP_052257806.1 hypothetical protein -
  ACFDHW_RS12625 (ACFDHW_12650) map 2516001..2516759 (-) 759 WP_107633460.1 type I methionyl aminopeptidase -
  ACFDHW_RS12630 (ACFDHW_12655) - 2517053..2518078 (+) 1026 WP_039644788.1 aromatic acid exporter family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23540.17 Da        Isoelectric Point: 5.1671

>NTDB_id=1055635 ACFDHW_RS12605 WP_039644795.1 2513143..2513772(-) (vraR) [Staphylococcus hyicus strain SC382]
MTIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGASGKEAITKAHELQPDLILMDLVMTDMDGVEATTQIKKDLPRIKVV
MLTSYIEDKEVYRALDAGVDSYILKTTSASDIAEAIRKTHKGESVFEAEVLVKMRNRMRQRAELYELLTEREMEILLLIS
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHGLIE

Nucleotide


Download         Length: 630 bp        

>NTDB_id=1055635 ACFDHW_RS12605 WP_039644795.1 2513143..2513772(-) (vraR) [Staphylococcus hyicus strain SC382]
ATGACAATTAAAGTATTATTTGTGGATGATCATGAAATGGTAAGAATTGGAATATCAAGTTATCTTTCAACTCAACCAGA
TATTGAAGTAGTTGGTGAAGGAGCATCGGGTAAAGAAGCGATTACGAAGGCGCATGAACTTCAACCGGATTTGATTTTAA
TGGACTTAGTGATGACAGATATGGATGGTGTAGAAGCGACGACTCAAATTAAAAAAGATTTACCACGTATTAAAGTCGTG
ATGCTTACAAGCTATATTGAAGATAAAGAAGTTTACCGTGCGTTAGATGCAGGGGTGGACAGTTATATATTAAAAACAAC
AAGTGCAAGCGATATAGCCGAAGCAATTCGTAAAACACATAAAGGTGAATCTGTTTTTGAAGCTGAAGTACTAGTGAAAA
TGCGAAATCGTATGAGACAAAGAGCAGAACTTTATGAATTATTAACGGAACGTGAAATGGAAATATTGTTACTGATTTCC
AAAGGTTACTCAAATCAGGAAATTGCGAGTGCCTCTCATATTACGATAAAGACGGTAAAAACGCATGTCAGTAACATTTT
AAGTAAGCTTGAAGTACAAGACCGTACACAAGCAGTTATTTATGCCTTTCAACATGGCTTAATTGAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0A8HRY9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

90.431

100

0.904
  degU Bacillus subtilis subsp. subtilis str. 168

35.714

100

0.383

Multiple sequence alignment