Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACE2AN_RS01885 Genome accession   NZ_CP169564
Coordinates   357191..357880 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 6_2F1     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 352191..362880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE2AN_RS01860 gpsB 352301..352630 (+) 330 WP_000146522.1 cell division regulator GpsB -
  ACE2AN_RS01870 - 353116..354273 (+) 1158 WP_000711388.1 class I SAM-dependent RNA methyltransferase -
  ACE2AN_RS01875 mapZ 354285..355679 (+) 1395 WP_000039304.1 mid-cell-anchored protein MapZ -
  ACE2AN_RS01880 gndA 355755..357179 (+) 1425 WP_000158788.1 NADP-dependent phosphogluconate dehydrogenase -
  ACE2AN_RS01885 covR 357191..357880 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  ACE2AN_RS01890 cbpC 357978..358994 (+) 1017 WP_000771103.1 choline-binding protein CbpC -
  ACE2AN_RS01895 mvk 359116..359994 (+) 879 WP_000163315.1 mevalonate kinase -
  ACE2AN_RS01900 mvaD 359976..360929 (+) 954 WP_000373461.1 diphosphomevalonate decarboxylase -
  ACE2AN_RS01905 - 360916..361923 (+) 1008 WP_000562412.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=1052165 ACE2AN_RS01885 WP_000518018.1 357191..357880(+) (covR) [Streptococcus pneumoniae strain 6_2F1]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1052165 ACE2AN_RS01885 WP_000518018.1 357191..357880(+) (covR) [Streptococcus pneumoniae strain 6_2F1]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment