Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ACE17W_RS05900 Genome accession   NZ_CP169562
Coordinates   1341277..1341936 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila strain Lp02     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1336277..1346936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACE17W_RS05885 (ACE17W_05885) - 1337077..1337736 (+) 660 WP_010948343.1 hypothetical protein -
  ACE17W_RS05890 (ACE17W_05890) lcl 1337904..1339385 (+) 1482 WP_010948344.1 collagen-like adhesin Lcl -
  ACE17W_RS05895 (ACE17W_05895) uvrC 1339409..1341265 (-) 1857 WP_010948345.1 excinuclease ABC subunit UvrC -
  ACE17W_RS05900 (ACE17W_05900) letA 1341277..1341936 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  ACE17W_RS05905 (ACE17W_05905) phhA 1342061..1342879 (-) 819 WP_010948347.1 phenylalanine 4-monooxygenase -
  ACE17W_RS05910 (ACE17W_05910) - 1343318..1344415 (+) 1098 WP_010948348.1 competence/damage-inducible protein A -
  ACE17W_RS05915 (ACE17W_05915) cgtA 1344374..1345399 (-) 1026 WP_010948349.1 Obg family GTPase CgtA -
  ACE17W_RS05920 (ACE17W_05920) rpmA 1345614..1345892 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  ACE17W_RS05925 (ACE17W_05925) rplU 1345905..1346216 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=1052101 ACE17W_RS05900 WP_011216518.1 1341277..1341936(-) (letA) [Legionella pneumophila strain Lp02]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1052101 ACE17W_RS05900 WP_011216518.1 1341277..1341936(-) (letA) [Legionella pneumophila strain Lp02]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTAAAAACCCACTCCCCTGATGTCGTATTATTAG
ATATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGTTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCT
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCAGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGTCTCAGGATTCCCCTTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment