Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   ACETWW_RS14680 Genome accession   NZ_CP169072
Coordinates   2999444..3000088 (-) Length   214 a.a.
NCBI ID   WP_003152052.1    Uniprot ID   A3KLB8
Organism   Bacillus velezensis strain T971     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 2994444..3005088
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACETWW_RS14645 (ACETWW_14635) - 2995629..2996060 (+) 432 WP_007408670.1 Na(+)/H(+) antiporter subunit B -
  ACETWW_RS14650 (ACETWW_14640) - 2996060..2996401 (+) 342 WP_003152063.1 Na(+)/H(+) antiporter subunit C -
  ACETWW_RS14655 (ACETWW_14645) - 2996394..2997875 (+) 1482 WP_076424452.1 Na+/H+ antiporter subunit D -
  ACETWW_RS14660 (ACETWW_14650) - 2997881..2998357 (+) 477 WP_007408672.1 Na+/H+ antiporter subunit E -
  ACETWW_RS14665 (ACETWW_14655) - 2998357..2998641 (+) 285 WP_012118311.1 Na(+)/H(+) antiporter subunit F1 -
  ACETWW_RS14670 (ACETWW_14660) mnhG 2998625..2998999 (+) 375 WP_003152056.1 monovalent cation/H(+) antiporter subunit G -
  ACETWW_RS14675 (ACETWW_14665) - 2999039..2999422 (-) 384 WP_012118312.1 hotdog fold thioesterase -
  ACETWW_RS14680 (ACETWW_14670) comA 2999444..3000088 (-) 645 WP_003152052.1 response regulator transcription factor Regulator
  ACETWW_RS14685 (ACETWW_14675) comP 3000169..3002475 (-) 2307 WP_374004610.1 sensor histidine kinase Regulator
  ACETWW_RS14690 (ACETWW_14680) comX 3002494..3002670 (-) 177 WP_015240484.1 competence pheromone ComX -
  ACETWW_RS14695 (ACETWW_14685) - 3002685..3003560 (-) 876 WP_025285191.1 polyprenyl synthetase family protein -
  ACETWW_RS14700 (ACETWW_14690) degQ 3003712..3003852 (-) 141 WP_003152043.1 degradation enzyme regulation protein DegQ Regulator
  ACETWW_RS14705 (ACETWW_14695) - 3004317..3004658 (+) 342 WP_342794125.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24271.68 Da        Isoelectric Point: 4.9953

>NTDB_id=1049757 ACETWW_RS14680 WP_003152052.1 2999444..3000088(-) (comA) [Bacillus velezensis strain T971]
MKKILVIDDHPAVMEGTKTILETDTNLSVDCLSPDASEQFVLRHDFSAYDLILMDLNLGDDISGIELSKKILKENPLCKI
IVYTGYEVEDYFEESIRAGLHGAISKTESKEKIMQYIYHVLNGQILVDFSYFKQLMTQQKTKTSSSPQSEQDRLTPRERH
ILQEVEKGLTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDNVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=1049757 ACETWW_RS14680 WP_003152052.1 2999444..3000088(-) (comA) [Bacillus velezensis strain T971]
ATGAAAAAGATACTAGTGATTGATGATCATCCGGCTGTCATGGAGGGCACCAAGACGATTCTGGAAACGGACACGAATCT
TTCTGTCGATTGCCTCAGTCCTGATGCCAGTGAACAATTCGTTCTCCGGCATGATTTTTCAGCTTACGATCTCATATTAA
TGGATTTAAATCTGGGTGATGACATCAGCGGCATAGAGCTTTCCAAGAAAATCTTAAAAGAGAATCCTCTCTGTAAAATC
ATTGTCTACACAGGCTATGAGGTTGAAGATTATTTTGAAGAATCCATCCGCGCGGGCCTGCATGGCGCCATCAGCAAAAC
CGAATCTAAAGAGAAAATCATGCAATACATATATCACGTGCTCAACGGACAGATTTTAGTTGATTTCTCCTATTTCAAAC
AGCTGATGACCCAGCAAAAAACAAAAACGTCTTCTTCCCCTCAAAGTGAGCAGGATCGGTTAACCCCGAGAGAGCGCCAT
ATTCTCCAAGAGGTCGAAAAAGGTTTGACCAATCAGGAAATCGCAGATGCGCTTCACTTAAGCAAGCGGTCAATTGAATA
CAGCCTGACGTCCATTTTTAACAAGCTGAATGTCGGCTCCCGCACTGAAGCGGTGCTGATCGCCAAGTCAGATAACGTAC
TATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLB8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

86.449

100

0.864

Multiple sequence alignment