Detailed information NTG1046462

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: R8803_RS22970
• Genome accession: NZ_OY754392
• Coordinates: 4689768..4690793 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli isolate F719
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4684768..4695793

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8803_RS22960 (FGAF719_44230)	rpmE	4686999..4687211 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
R8803_RS22965 (FGAF719_44240)	priA	4687414..4689612 (+)	2199	WP_001325632.1	primosomal protein N'	Machinery gene
R8803_RS22970 (FGAF719_44250)	cytR	4689768..4690793 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
R8803_RS22975 (FGAF719_44260)	ftsN	4690885..4691844 (+)	960	WP_000068834.1	cell division protein FtsN	-
R8803_RS22980 (FGAF719_44270)	hslV	4691937..4692467 (+)	531	WP_000208243.1	ATP-dependent protease subunit HslV	-
R8803_RS22985 (FGAF719_44280)	hslU	4692477..4693808 (+)	1332	WP_001293343.1	HslU--HslV peptidase ATPase subunit	-
R8803_RS22990 (FGAF719_44290)	menA	4693875..4694801 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
R8803_RS22995 (FGAF719_44300)	rraA	4694894..4695379 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
R8803_RS23000 (FGAF719_44310)	zapB	4695464..4695709 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=1046462 R8803_RS22970 WP_000644904.1 4689768..4690793(+) (cytR) [Escherichia coli isolate F719]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=1046462 R8803_RS22970 WP_000644904.1 4689768..4690793(+) (cytR) [Escherichia coli isolate F719]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTCGCACCGGAACTGGAG
CTACCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATCTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGTTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628