Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACEPWM_RS02445 Genome accession   NZ_CP168642
Coordinates   526138..526707 (+) Length   189 a.a.
NCBI ID   WP_000872872.1    Uniprot ID   A0AB73JJN0
Organism   Staphylococcus aureus strain NCCP11854     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 521138..531707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEPWM_RS02420 (ACEPWM_02420) cysE 522351..522998 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  ACEPWM_RS02425 (ACEPWM_02425) cysS 522982..524382 (+) 1401 WP_000631977.1 cysteine--tRNA ligase -
  ACEPWM_RS02430 (ACEPWM_02430) - 524375..524779 (+) 405 WP_000370186.1 Mini-ribonuclease 3 -
  ACEPWM_RS02435 (ACEPWM_02435) rlmB 524787..525533 (+) 747 WP_000390339.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACEPWM_RS02440 (ACEPWM_02440) - 525533..526057 (+) 525 WP_000664738.1 NYN domain-containing protein -
  ACEPWM_RS02445 (ACEPWM_02445) sigH 526138..526707 (+) 570 WP_000872872.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACEPWM_RS02450 (ACEPWM_02450) rpmG 526822..526965 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACEPWM_RS02455 (ACEPWM_02455) secE 527021..527203 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACEPWM_RS02460 (ACEPWM_02460) nusG 527216..527764 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACEPWM_RS02465 (ACEPWM_02465) rplK 527945..528367 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACEPWM_RS02470 (ACEPWM_02470) rplA 528575..529267 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACEPWM_RS02475 (ACEPWM_02475) rplJ 529539..530039 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACEPWM_RS02480 (ACEPWM_02480) rplL 530082..530450 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACEPWM_RS02485 (ACEPWM_02485) - 530625..531233 (+) 609 WP_000020296.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23079.92 Da        Isoelectric Point: 9.6015

>NTDB_id=1044629 ACEPWM_RS02445 WP_000872872.1 526138..526707(+) (sigH) [Staphylococcus aureus strain NCCP11854]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRIDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1044629 ACEPWM_RS02445 WP_000872872.1 526138..526707(+) (sigH) [Staphylococcus aureus strain NCCP11854]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAACAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATAGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAGCGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

98.942

100

0.989
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment