Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   ACD268_RS09535 Genome accession   NZ_CP168299
Coordinates   1860816..1861436 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain FC1     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1855816..1866436
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD268_RS09510 (ACD268_09510) recA 1856193..1857359 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  ACD268_RS09515 (ACD268_09515) cinA 1857414..1858670 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  ACD268_RS09520 (ACD268_09520) - 1858755..1859771 (-) 1017 WP_000239278.1 LCP family protein -
  ACD268_RS09525 (ACD268_09525) - 1859779..1860297 (-) 519 WP_044788611.1 GNAT family N-acetyltransferase -
  ACD268_RS09530 (ACD268_09530) tsaE 1860287..1860730 (-) 444 WP_061388823.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ACD268_RS09535 (ACD268_09535) comM 1860816..1861436 (-) 621 WP_000839908.1 hypothetical protein Regulator
  ACD268_RS09540 (ACD268_09540) - 1861819..1862682 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  ACD268_RS09545 (ACD268_09545) - 1862855..1863028 (+) 174 WP_050365367.1 PhrA family quorum-sensing system peptide -
  ACD268_RS09550 (ACD268_09550) - 1863478..1865493 (+) 2016 WP_050365366.1 DUF1430 domain-containing protein -
  ACD268_RS09555 (ACD268_09555) - 1865495..1866127 (+) 633 WP_000571415.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=1043738 ACD268_RS09535 WP_000839908.1 1860816..1861436(-) (comM) [Streptococcus pneumoniae strain FC1]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=1043738 ACD268_RS09535 WP_000839908.1 1860816..1861436(-) (comM) [Streptococcus pneumoniae strain FC1]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment