Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   ACD268_RS03590 Genome accession   NZ_CP168299
Coordinates   686883..688115 (+) Length   410 a.a.
NCBI ID   WP_025170138.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 681883..693115
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD268_RS03560 (ACD268_03560) - 681947..682624 (+) 678 WP_000221584.1 DnaD domain-containing protein -
  ACD268_RS03565 (ACD268_03565) tpiA 682722..683480 (+) 759 WP_000087897.1 triose-phosphate isomerase -
  ACD268_RS03570 (ACD268_03570) lytC 683518..685022 (+) 1505 Protein_704 choline binding-anchored murein hydrolase LytC -
  ACD268_RS03575 (ACD268_03575) - 685518..686036 (+) 519 WP_000229873.1 DNA starvation/stationary phase protection protein -
  ACD268_RS03580 (ACD268_03580) - 686166..686672 (+) 507 WP_138001137.1 dihydrofolate reductase -
  ACD268_RS03585 (ACD268_03585) - 686672..686842 (+) 171 WP_000442277.1 hypothetical protein -
  ACD268_RS03590 (ACD268_03590) clpX 686883..688115 (+) 1233 WP_025170138.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  ACD268_RS03595 (ACD268_03595) yihA 688124..688711 (+) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  ACD268_RS03600 (ACD268_03600) - 688722..689102 (+) 381 WP_001140412.1 RidA family protein -
  ACD268_RS03605 (ACD268_03605) rapZ 689154..690044 (+) 891 WP_000163033.1 RNase adapter RapZ -
  ACD268_RS03610 (ACD268_03610) - 690041..691018 (+) 978 WP_001231086.1 YvcK family protein -
  ACD268_RS03615 (ACD268_03615) whiA 691015..691926 (+) 912 WP_000011276.1 DNA-binding protein WhiA -
  ACD268_RS03620 (ACD268_03620) - 691960..692928 (-) 969 WP_000081003.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45781.32 Da        Isoelectric Point: 4.4240

>NTDB_id=1043705 ACD268_RS03590 WP_025170138.1 686883..688115(+) (clpX) [Streptococcus pneumoniae strain FC1]
MPTTRNNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1043705 ACD268_RS03590 WP_025170138.1 686883..688115(+) (clpX) [Streptococcus pneumoniae strain FC1]
ATGCCTACAACTAGGAATAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAATCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTCTGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACCGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTTGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.341

100

0.863
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.214

98.049

0.561

Multiple sequence alignment