Detailed information NTG1043523

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ACD269_RS09385
• Genome accession: NZ_CP168260
• Coordinates: 1823996..1825033 (-)
• Length: 345 a.a.
• NCBI ID: WP_012677144.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain FC2
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1818996..1830033

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACD269_RS09360 (ACD269_09360)	-	1819797..1821128 (-)	1332	WP_373380537.1	hemolysin family protein	-
ACD269_RS09365 (ACD269_09365)	endA	1821357..1822181 (-)	825	WP_001036779.1	DNA-entry nuclease EndA	Machinery gene
ACD269_RS09370 (ACD269_09370)	-	1822220..1822408 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
ACD269_RS09375 (ACD269_09375)	murA	1822401..1823684 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
ACD269_RS09380 (ACD269_09380)	-	1823708..1823938 (-)	231	WP_000250392.1	DUF1146 family protein	-
ACD269_RS09385 (ACD269_09385)	sepM	1823996..1825033 (-)	1038	WP_012677144.1	SepM family pheromone-processing serine protease	Regulator
ACD269_RS09390 (ACD269_09390)	coaD	1825017..1825505 (-)	489	WP_001280753.1	pantetheine-phosphate adenylyltransferase	-
ACD269_RS09395 (ACD269_09395)	rsmD	1825495..1826034 (-)	540	WP_001819515.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ACD269_RS09400 (ACD269_09400)	asnA	1826099..1827091 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
ACD269_RS09405 (ACD269_09405)	-	1827203..1827886 (-)	684	WP_001016917.1	Bax inhibitor-1/YccA family protein	-
ACD269_RS09410 (ACD269_09410)	-	1827942..1828682 (-)	741	WP_000152678.1	RNA methyltransferase	-
ACD269_RS09415 (ACD269_09415)	-	1828716..1828994 (+)	279	WP_001174613.1	acylphosphatase	-
ACD269_RS09420 (ACD269_09420)	yidC	1829072..1829998 (+)	927	WP_000835955.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37549.57 Da
• Isoelectric Point: 5.0724

>NTDB_id=1043523 ACD269_RS09385 WP_012677144.1 1823996..1825033(-) (sepM) [Streptococcus pneumoniae strain FC2]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFLRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFTPDNPVSEEEQKAHPDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=1043523 ACD269_RS09385 WP_012677144.1 1823996..1825033(-) (sepM) [Streptococcus pneumoniae strain FC2]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTCTGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTACTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588