Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   ACD269_RS09365 Genome accession   NZ_CP168260
Coordinates   1821357..1822181 (-) Length   274 a.a.
NCBI ID   WP_001036779.1    Uniprot ID   P0A3S3
Organism   Streptococcus pneumoniae strain FC2     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1816357..1827181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD269_RS09360 (ACD269_09360) - 1819797..1821128 (-) 1332 WP_373380537.1 hemolysin family protein -
  ACD269_RS09365 (ACD269_09365) endA 1821357..1822181 (-) 825 WP_001036779.1 DNA-entry nuclease EndA Machinery gene
  ACD269_RS09370 (ACD269_09370) - 1822220..1822408 (-) 189 WP_001813390.1 DNA-directed RNA polymerase subunit beta -
  ACD269_RS09375 (ACD269_09375) murA 1822401..1823684 (-) 1284 WP_000358028.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  ACD269_RS09380 (ACD269_09380) - 1823708..1823938 (-) 231 WP_000250392.1 DUF1146 family protein -
  ACD269_RS09385 (ACD269_09385) sepM 1823996..1825033 (-) 1038 WP_012677144.1 SepM family pheromone-processing serine protease Regulator
  ACD269_RS09390 (ACD269_09390) coaD 1825017..1825505 (-) 489 WP_001280753.1 pantetheine-phosphate adenylyltransferase -
  ACD269_RS09395 (ACD269_09395) rsmD 1825495..1826034 (-) 540 WP_001819515.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ACD269_RS09400 (ACD269_09400) asnA 1826099..1827091 (-) 993 WP_000747993.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29890.57 Da        Isoelectric Point: 10.1197

>NTDB_id=1043522 ACD269_RS09365 WP_001036779.1 1821357..1822181(-) (endA) [Streptococcus pneumoniae strain FC2]
MNKKTRQTLIGLLVLLLLSTGSYYIKQMPSAPNSPKTNLSQKKQASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1043522 ACD269_RS09365 WP_001036779.1 1821357..1822181(-) (endA) [Streptococcus pneumoniae strain FC2]
ATGAACAAAAAAACAAGACAGACACTAATCGGACTGCTAGTGTTATTGCTTTTGTCTACAGGGAGCTATTATATCAAGCA
GATGCCGTCGGCACCTAATAGTCCCAAAACCAATCTTAGTCAGAAAAAACAAGCGTCTGAAGCTCCTAGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAGAGTCAAATAAAGGGGAGTCTGGAGTGGAATGGCTCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAATCTAGATGCCAAGGTTTCAAGTAAGCCCTACGCTGACAATAAAACAAAGACAGTGGGCAAGGA
AACTGTTCCAACCGTAGCTAATGCCCTCTTGTCTAAGGCCACTCGTCAGTACAAGAATCGTAAAGAAACTGGGAATGGTT
CAACTTCTTGGACTCCTCCAGGTTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
TTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCAACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCACAAGCCGAGTATTCGACTGGTCAAAACTACTATGAAAGCAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCCTCAGCTTCACAGATTGAA
GCCAAGTCTTCGGATGGAGAATTGGAATTCAATGTTCTAGTTCCCAATGTTCAAAAGGGACTTCAACTGGATTACCGAAC
TGGAGAAGTAACTGTAACTCAGTAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3OWV

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

100

100

1
  endA Streptococcus pneumoniae D39

100

100

1
  endA Streptococcus pneumoniae R6

100

100

1
  endA Streptococcus pneumoniae TIGR4

100

100

1

Multiple sequence alignment