Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   ACD269_RS01885 Genome accession   NZ_CP168260
Coordinates   361180..361869 (+) Length   229 a.a.
NCBI ID   WP_000518011.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC2     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 356180..366869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD269_RS01860 (ACD269_01860) gpsB 356290..356619 (+) 330 WP_000146522.1 cell division regulator GpsB -
  ACD269_RS01870 (ACD269_01870) - 357105..358262 (+) 1158 WP_050210510.1 class I SAM-dependent RNA methyltransferase -
  ACD269_RS01875 (ACD269_01875) mapZ 358274..359668 (+) 1395 WP_000039304.1 mid-cell-anchored protein MapZ -
  ACD269_RS01880 (ACD269_01880) gndA 359744..361168 (+) 1425 WP_050210509.1 NADP-dependent phosphogluconate dehydrogenase -
  ACD269_RS01885 (ACD269_01885) covR 361180..361869 (+) 690 WP_000518011.1 response regulator transcription factor Regulator
  ACD269_RS01890 (ACD269_01890) cbpC 361967..362923 (+) 957 WP_050210508.1 choline-binding protein CbpC -
  ACD269_RS01895 (ACD269_01895) - 363041..364273 (-) 1233 WP_373380777.1 MFS transporter -
  ACD269_RS01900 (ACD269_01900) - 364284..364904 (-) 621 WP_041172747.1 lanthionine synthetase LanC family protein -
  ACD269_RS01905 (ACD269_01905) - 364804..365193 (-) 390 WP_196301600.1 lanthionine synthetase LanC family protein -
  ACD269_RS01910 (ACD269_01910) - 365805..365972 (+) 168 Protein_373 transposase -
  ACD269_RS01915 (ACD269_01915) - 366012..366134 (+) 123 Protein_374 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26880.19 Da        Isoelectric Point: 6.9836

>NTDB_id=1043478 ACD269_RS01885 WP_000518011.1 361180..361869(+) (covR) [Streptococcus pneumoniae strain FC2]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1043478 ACD269_RS01885 WP_000518011.1 361180..361869(+) (covR) [Streptococcus pneumoniae strain FC2]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGCCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGACAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment