Detailed information NTG0104293

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: Q433_RS00590
• Genome accession: NZ_CP007409
• Coordinates: 107373..108455 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis subsp. subtilis str. OH 131.1 strain OH131.1
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 102373..113455

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q433_RS00575 (Q433_00595)	mcsB	102381..103472 (+)	1092	WP_038427264.1	protein arginine kinase	-
Q433_RS00580 (Q433_00600)	clpC	103469..105901 (+)	2433	WP_038427265.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
Q433_RS00585 (Q433_00605)	radA/sms	105993..107369 (+)	1377	WP_015252992.1	DNA repair protein RadA	Machinery gene
Q433_RS00590 (Q433_00610)	disA	107373..108455 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
Q433_RS00595 (Q433_00615)	yacL	108571..109671 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
Q433_RS00600 (Q433_00620)	ispD	109686..110384 (+)	699	WP_038427266.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
Q433_RS00605 (Q433_00625)	ispF	110377..110853 (+)	477	WP_014475594.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
Q433_RS00610 (Q433_00630)	gltX	110944..112395 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
Q433_RS00620 (Q433_00640)	cysE	112697..113350 (+)	654	WP_003225749.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=104293 Q433_RS00590 WP_003225736.1 107373..108455(+) (disA) [Bacillus subtilis subsp. subtilis str. OH 131.1 strain OH131.1]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=104293 Q433_RS00590 WP_003225736.1 107373..108455(+) (disA) [Bacillus subtilis subsp. subtilis str. OH 131.1 strain OH131.1]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTTCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1