Detailed information NTG1042821

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACCK26_RS04460
• Genome accession: NZ_CP168160
• Coordinates: 939033..940019 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain CUBIST-33
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 934033..945019

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK26_RS04435 (ACCK26_04435)	opp4B	934247..935209 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACCK26_RS04440 (ACCK26_04440)	opp4C	935221..936102 (+)	882	WP_373334229.1	oligopeptide ABC transporter permease	-
ACCK26_RS04445 (ACCK26_04445)	trpS	936144..937133 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACCK26_RS04450 (ACCK26_04450)	spxA	937427..937822 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACCK26_RS04455 (ACCK26_04455)	mecA	938193..938912 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACCK26_RS04460 (ACCK26_04460)	coiA	939033..940019 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACCK26_RS04465 (ACCK26_04465)	pepF	940067..941875 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACCK26_RS04470 (ACCK26_04470)	yjbH	942335..943141 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACCK26_RS04475 (ACCK26_04475)	-	943164..943529 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACCK26_RS04480 (ACCK26_04480)	-	943633..944226 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACCK26_RS04485 (ACCK26_04485)	-	944412..944759 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1042821 ACCK26_RS04460 WP_000959282.1 939033..940019(+) (coiA) [Staphylococcus aureus strain CUBIST-33]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1042821 ACCK26_RS04460 WP_000959282.1 939033..940019(+) (coiA) [Staphylococcus aureus strain CUBIST-33]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976