Detailed information NTG1042690

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACCK24_RS04595
• Genome accession: NZ_CP168154
• Coordinates: 969185..970171 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain CUBIST-6
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 964185..975171

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK24_RS04570 (ACCK24_04570)	opp4B	964399..965361 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACCK24_RS04575 (ACCK24_04575)	opp4C	965373..966254 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACCK24_RS04580 (ACCK24_04580)	trpS	966296..967285 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACCK24_RS04585 (ACCK24_04585)	spxA	967579..967974 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACCK24_RS04590 (ACCK24_04590)	mecA	968345..969064 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACCK24_RS04595 (ACCK24_04595)	coiA	969185..970171 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACCK24_RS04600 (ACCK24_04600)	pepF	970219..972027 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACCK24_RS04605 (ACCK24_04605)	yjbH	972487..973293 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACCK24_RS04610 (ACCK24_04610)	-	973316..973681 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACCK24_RS04615 (ACCK24_04615)	-	973785..974378 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACCK24_RS04620 (ACCK24_04620)	-	974564..974911 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1042690 ACCK24_RS04595 WP_000959282.1 969185..970171(+) (coiA) [Staphylococcus aureus strain CUBIST-6]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1042690 ACCK24_RS04595 WP_000959282.1 969185..970171(+) (coiA) [Staphylococcus aureus strain CUBIST-6]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976