Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ACCK25_RS13365 Genome accession   NZ_CP168096
Coordinates   2678824..2679489 (-) Length   221 a.a.
NCBI ID   WP_000697877.1    Uniprot ID   A0A0D1JN68
Organism   Staphylococcus aureus strain CUBIST-51     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2673824..2684489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACCK25_RS13345 (ACCK25_13345) - 2674294..2674407 (-) 114 Protein_2556 hypothetical protein -
  ACCK25_RS13350 (ACCK25_13350) - 2675066..2677066 (-) 2001 WP_000776750.1 ABC transporter permease -
  ACCK25_RS13355 (ACCK25_13355) - 2677063..2677818 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  ACCK25_RS13360 (ACCK25_13360) braS 2677926..2678813 (-) 888 WP_000143425.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  ACCK25_RS13365 (ACCK25_13365) braR 2678824..2679489 (-) 666 WP_000697877.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  ACCK25_RS13370 (ACCK25_13370) - 2679515..2679715 (-) 201 WP_000604730.1 hypothetical protein -
  ACCK25_RS13375 (ACCK25_13375) - 2679913..2681337 (+) 1425 Protein_2562 alkaline phosphatase -
  ACCK25_RS13380 (ACCK25_13380) - 2681397..2681498 (-) 102 WP_000731976.1 SE2200 family small protein -
  ACCK25_RS13385 (ACCK25_13385) - 2681620..2682075 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  ACCK25_RS13390 (ACCK25_13390) - 2682320..2683081 (-) 762 WP_000323441.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25415.49 Da        Isoelectric Point: 4.7961

>NTDB_id=1042155 ACCK25_RS13365 WP_000697877.1 2678824..2679489(-) (braR) [Staphylococcus aureus strain CUBIST-51]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1042155 ACCK25_RS13365 WP_000697877.1 2678824..2679489(-) (braR) [Staphylococcus aureus strain CUBIST-51]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-111)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D1JN68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

100

100

1

Multiple sequence alignment