Detailed information NTG1042154

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK25_RS13360
• Genome accession: NZ_CP168096
• Coordinates: 2677926..2678813 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain CUBIST-51
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2672926..2683813

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK25_RS13330 (ACCK25_13330)	-	2672945..2673037 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK25_RS13335 (ACCK25_13335)	-	2673145..2673642 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK25_RS13340 (ACCK25_13340)	-	2673652..2673912 (-)	261	WP_001791974.1	hypothetical protein	-
ACCK25_RS13345 (ACCK25_13345)	-	2674294..2674407 (-)	114	Protein_2556	hypothetical protein	-
ACCK25_RS13350 (ACCK25_13350)	-	2675066..2677066 (-)	2001	WP_000776750.1	ABC transporter permease	-
ACCK25_RS13355 (ACCK25_13355)	-	2677063..2677818 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK25_RS13360 (ACCK25_13360)	braS	2677926..2678813 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK25_RS13365 (ACCK25_13365)	braR	2678824..2679489 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK25_RS13370 (ACCK25_13370)	-	2679515..2679715 (-)	201	WP_000604730.1	hypothetical protein	-
ACCK25_RS13375 (ACCK25_13375)	-	2679913..2681337 (+)	1425	Protein_2562	alkaline phosphatase	-
ACCK25_RS13380 (ACCK25_13380)	-	2681397..2681498 (-)	102	WP_000731976.1	SE2200 family small protein	-
ACCK25_RS13385 (ACCK25_13385)	-	2681620..2682075 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK25_RS13390 (ACCK25_13390)	-	2682320..2683081 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1042154 ACCK25_RS13360 WP_000143425.1 2677926..2678813(-) (braS) [Staphylococcus aureus strain CUBIST-51]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1042154 ACCK25_RS13360 WP_000143425.1 2677926..2678813(-) (braS) [Staphylococcus aureus strain CUBIST-51]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1