Detailed information NTG1042126

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACCK25_RS04720
• Genome accession: NZ_CP168096
• Coordinates: 964092..965078 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain CUBIST-51
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 959092..970078

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK25_RS04695 (ACCK25_04695)	opp4B	959306..960268 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACCK25_RS04700 (ACCK25_04700)	opp4C	960280..961161 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACCK25_RS04705 (ACCK25_04705)	trpS	961203..962192 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACCK25_RS04710 (ACCK25_04710)	spxA	962486..962881 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACCK25_RS04715 (ACCK25_04715)	mecA	963252..963971 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACCK25_RS04720 (ACCK25_04720)	coiA	964092..965078 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACCK25_RS04725 (ACCK25_04725)	pepF	965126..966934 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACCK25_RS04730 (ACCK25_04730)	yjbH	967394..968200 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACCK25_RS04735 (ACCK25_04735)	-	968223..968588 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACCK25_RS04740 (ACCK25_04740)	-	968692..969285 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACCK25_RS04745 (ACCK25_04745)	-	969471..969818 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1042126 ACCK25_RS04720 WP_000959282.1 964092..965078(+) (coiA) [Staphylococcus aureus strain CUBIST-51]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1042126 ACCK25_RS04720 WP_000959282.1 964092..965078(+) (coiA) [Staphylococcus aureus strain CUBIST-51]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976