Detailed information NTG1041955

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACCK22_RS05500
• Genome accession: NZ_CP168085
• Coordinates: 1086569..1087555 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain CUBIST-27
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1081569..1092555

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK22_RS05475 (ACCK22_05475)	opp4B	1081783..1082745 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACCK22_RS05480 (ACCK22_05480)	opp4C	1082757..1083638 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACCK22_RS05485 (ACCK22_05485)	trpS	1083680..1084669 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACCK22_RS05490 (ACCK22_05490)	spxA	1084963..1085358 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACCK22_RS05495 (ACCK22_05495)	mecA	1085729..1086448 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACCK22_RS05500 (ACCK22_05500)	coiA	1086569..1087555 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACCK22_RS05505 (ACCK22_05505)	pepF	1087603..1089411 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
ACCK22_RS05510 (ACCK22_05510)	yjbH	1089871..1090677 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACCK22_RS05515 (ACCK22_05515)	-	1090700..1091065 (-)	366	WP_064134835.1	truncated hemoglobin YjbI	-
ACCK22_RS05520 (ACCK22_05520)	-	1091169..1091762 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACCK22_RS05525 (ACCK22_05525)	-	1091948..1092295 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1041955 ACCK22_RS05500 WP_000959282.1 1086569..1087555(+) (coiA) [Staphylococcus aureus strain CUBIST-27]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1041955 ACCK22_RS05500 WP_000959282.1 1086569..1087555(+) (coiA) [Staphylococcus aureus strain CUBIST-27]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976