Detailed information NTG1041108

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: ACDZ06_RS04475
• Genome accession: NZ_CP168010
• Coordinates: 931192..932178 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain sa231003_barcode77
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 926192..937178

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACDZ06_RS04450 (ACDZ06_04450)	opp4B	926406..927368 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
ACDZ06_RS04455 (ACDZ06_04455)	opp4C	927380..928261 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
ACDZ06_RS04460 (ACDZ06_04460)	trpS	928303..929292 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
ACDZ06_RS04465 (ACDZ06_04465)	spxA	929586..929981 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
ACDZ06_RS04470 (ACDZ06_04470)	mecA	930352..931071 (+)	720	WP_001217728.1	adaptor protein MecA	-
ACDZ06_RS04475 (ACDZ06_04475)	coiA	931192..932178 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
ACDZ06_RS04480 (ACDZ06_04480)	pepF	932226..934034 (+)	1809	WP_168751494.1	oligoendopeptidase F	-
ACDZ06_RS04485 (ACDZ06_04485)	yjbH	934494..935300 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
ACDZ06_RS04490 (ACDZ06_04490)	-	935323..935688 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
ACDZ06_RS04495 (ACDZ06_04495)	-	935792..936385 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
ACDZ06_RS04500 (ACDZ06_04500)	-	936571..936918 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=1041108 ACDZ06_RS04475 WP_000959282.1 931192..932178(+) (coiA) [Staphylococcus aureus strain sa231003_barcode77]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=1041108 ACDZ06_RS04475 WP_000959282.1 931192..932178(+) (coiA) [Staphylococcus aureus strain sa231003_barcode77]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976