Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ACCK12_RS13875 Genome accession   NZ_CP167990
Coordinates   2756703..2757368 (-) Length   221 a.a.
NCBI ID   WP_000697886.1    Uniprot ID   A0A0D3QBD0
Organism   Staphylococcus aureus strain CUBIST-4     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2751703..2762368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACCK12_RS13855 (ACCK12_13855) - 2752173..2752286 (-) 114 WP_001791776.1 hypothetical protein -
  ACCK12_RS13860 (ACCK12_13860) - 2752945..2754945 (-) 2001 WP_000776751.1 ABC transporter permease -
  ACCK12_RS13865 (ACCK12_13865) - 2754942..2755697 (-) 756 WP_000923760.1 ABC transporter ATP-binding protein -
  ACCK12_RS13870 (ACCK12_13870) braS 2755805..2756692 (-) 888 WP_000143419.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  ACCK12_RS13875 (ACCK12_13875) braR 2756703..2757368 (-) 666 WP_000697886.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  ACCK12_RS13880 (ACCK12_13880) - 2757394..2757594 (-) 201 WP_000604728.1 hypothetical protein -
  ACCK12_RS13885 (ACCK12_13885) - 2757792..2759216 (+) 1425 WP_000953744.1 alkaline phosphatase -
  ACCK12_RS13890 (ACCK12_13890) - 2759276..2759377 (-) 102 WP_000731972.1 SE2200 family small protein -
  ACCK12_RS13895 (ACCK12_13895) - 2759499..2759954 (-) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  ACCK12_RS13900 (ACCK12_13900) - 2760199..2760960 (-) 762 WP_000323455.1 alpha/beta hydrolase family protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25392.45 Da        Isoelectric Point: 4.6846

>NTDB_id=1040956 ACCK12_RS13875 WP_000697886.1 2756703..2757368(-) (braR) [Staphylococcus aureus strain CUBIST-4]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQNQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSLTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=1040956 ACCK12_RS13875 WP_000697886.1 2756703..2757368(-) (braR) [Staphylococcus aureus strain CUBIST-4]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAGAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAAAATCAACCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAGCCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCATTGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D3QBD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995

Multiple sequence alignment