Detailed information NTG1040955

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: ACCK12_RS13870
• Genome accession: NZ_CP167990
• Coordinates: 2755805..2756692 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain CUBIST-4
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2750805..2761692

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACCK12_RS13840 (ACCK12_13840)	-	2750824..2750916 (+)	93	WP_010956583.1	hypothetical protein	-
ACCK12_RS13845 (ACCK12_13845)	-	2751024..2751521 (-)	498	WP_001065268.1	glutathione peroxidase	-
ACCK12_RS13850 (ACCK12_13850)	-	2751531..2751791 (-)	261	WP_001789910.1	hypothetical protein	-
ACCK12_RS13855 (ACCK12_13855)	-	2752173..2752286 (-)	114	WP_001791776.1	hypothetical protein	-
ACCK12_RS13860 (ACCK12_13860)	-	2752945..2754945 (-)	2001	WP_000776751.1	ABC transporter permease	-
ACCK12_RS13865 (ACCK12_13865)	-	2754942..2755697 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
ACCK12_RS13870 (ACCK12_13870)	braS	2755805..2756692 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
ACCK12_RS13875 (ACCK12_13875)	braR	2756703..2757368 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
ACCK12_RS13880 (ACCK12_13880)	-	2757394..2757594 (-)	201	WP_000604728.1	hypothetical protein	-
ACCK12_RS13885 (ACCK12_13885)	-	2757792..2759216 (+)	1425	WP_000953744.1	alkaline phosphatase	-
ACCK12_RS13890 (ACCK12_13890)	-	2759276..2759377 (-)	102	WP_000731972.1	SE2200 family small protein	-
ACCK12_RS13895 (ACCK12_13895)	-	2759499..2759954 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
ACCK12_RS13900 (ACCK12_13900)	-	2760199..2760960 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1040955 ACCK12_RS13870 WP_000143419.1 2755805..2756692(-) (braS) [Staphylococcus aureus strain CUBIST-4]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1040955 ACCK12_RS13870 WP_000143419.1 2755805..2756692(-) (braS) [Staphylococcus aureus strain CUBIST-4]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997