Detailed information    

insolico Bioinformatically predicted

Overview

Name   comP   Type   Machinery gene
Locus tag   ACDK45_RS03225 Genome accession   NZ_CP167879
Coordinates   626822..627505 (+) Length   227 a.a.
NCBI ID   WP_011272301.1    Uniprot ID   Q4QLW8
Organism   Haemophilus influenzae strain NTHi52     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 621822..632505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACDK45_RS03200 (ACDK45_03200) - 622037..622567 (-) 531 WP_005688388.1 DsbE family thiol:disulfide interchange protein -
  ACDK45_RS03205 (ACDK45_03205) nrfE 622567..624473 (-) 1907 Protein_602 heme lyase NrfEFG subunit NrfE -
  ACDK45_RS03210 (ACDK45_03210) suhB 624582..625394 (-) 813 WP_011272298.1 inositol-1-monophosphatase -
  ACDK45_RS03215 (ACDK45_03215) comN 625594..626106 (+) 513 WP_011272299.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  ACDK45_RS03220 (ACDK45_03220) comO 626106..626825 (+) 720 WP_011272300.1 type II secretion system protein J Machinery gene
  ACDK45_RS03225 (ACDK45_03225) comP 626822..627505 (+) 684 WP_011272301.1 DUF2572 family protein Machinery gene
  ACDK45_RS03230 (ACDK45_03230) comQ 627498..627785 (+) 288 WP_021034778.1 DUF5374 domain-containing protein Machinery gene
  ACDK45_RS03235 (ACDK45_03235) recC 627831..631196 (+) 3366 WP_044364474.1 exodeoxyribonuclease V subunit gamma -
  ACDK45_RS03240 (ACDK45_03240) nrdR 631251..631700 (+) 450 WP_005651549.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 227 a.a.        Molecular weight: 25371.21 Da        Isoelectric Point: 9.5157

>NTDB_id=1040085 ACDK45_RS03225 WP_011272301.1 626822..627505(+) (comP) [Haemophilus influenzae strain NTHi52]
MTIQKGIITLTILIFISGLLSVILLLDDSNLSFFRAQQNQRKLYVERTLQLQRITALKKQTACLDLSLNNDESVKQISIT
LDGATDSIQYFLWCERMSLFKKSPKKGDNQGALKDFVSGEKLAYFRPHFSSPPRILNANKTPKLYWFSDSQAEVEINGTV
SAVLIAEGDLKLTGKGRISGAVITNGNLTLDGVTLAYGKKTVVALVQQYSQWKLAEKSWSDFNVQDE

Nucleotide


Download         Length: 684 bp        

>NTDB_id=1040085 ACDK45_RS03225 WP_011272301.1 626822..627505(+) (comP) [Haemophilus influenzae strain NTHi52]
ATGACAATACAAAAAGGTATTATTACGCTGACTATTCTGATTTTTATTTCAGGCTTATTAAGCGTAATCTTATTGTTAGA
TGATAGCAATTTAAGTTTTTTTCGGGCGCAACAAAATCAACGAAAACTGTATGTGGAAAGAACATTACAATTACAAAGAA
TAACAGCCTTGAAAAAACAAACTGCCTGCCTTGATTTATCATTAAATAATGATGAAAGTGTAAAGCAAATCAGCATTACG
CTTGATGGTGCCACAGATTCAATTCAATATTTTCTTTGGTGTGAAAGAATGAGCCTATTTAAAAAATCGCCTAAAAAGGG
AGATAATCAAGGCGCATTGAAAGATTTTGTGAGTGGCGAAAAACTTGCCTATTTTCGACCGCACTTTTCTTCTCCGCCCA
GAATTTTAAACGCGAATAAAACGCCTAAACTTTATTGGTTTTCAGATTCACAAGCAGAGGTTGAAATTAATGGCACGGTG
TCTGCCGTATTAATTGCAGAGGGCGATTTAAAATTGACTGGCAAAGGGAGGATTAGTGGCGCAGTGATTACCAACGGGAA
TTTAACTTTAGATGGCGTAACTTTAGCTTATGGGAAAAAGACGGTGGTCGCTTTAGTGCAACAATATAGTCAGTGGAAGT
TAGCAGAAAAAAGTTGGAGTGATTTTAATGTTCAGGATGAATAA

Domains

Predicted by InterproScan.

Protein of unknown function (DUF2572) (DUF2572)

(5-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comP Haemophilus influenzae Rd KW20

91.63

100

0.916

Multiple sequence alignment