Detailed information NTG1038137

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACB345_RS03500
• Genome accession: NZ_CP167025
• Coordinates: 684357..685586 (+)
• Length: 409 a.a.
• NCBI ID: WP_031488352.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 679357..690586

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB345_RS03480 (ACB345_03480)	-	679973..681250 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACB345_RS03485 (ACB345_03485)	-	681237..682412 (-)	1176	WP_031488354.1	hydroxymethylglutaryl-CoA synthase	-
ACB345_RS03490 (ACB345_03490)	-	682621..683460 (+)	840	WP_011017679.1	thymidylate synthase	-
ACB345_RS03495 (ACB345_03495)	-	683540..684037 (+)	498	WP_031488353.1	dihydrofolate reductase	-
ACB345_RS03500 (ACB345_03500)	clpX	684357..685586 (+)	1230	WP_031488352.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACB345_RS03505 (ACB345_03505)	yihA	685596..686195 (+)	600	WP_002990160.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ACB345_RS03510 (ACB345_03510)	-	686343..687086 (+)	744	WP_002984942.1	hypothetical protein	-
ACB345_RS03515 (ACB345_03515)	-	687144..689243 (-)	2100	WP_031488351.1	AAA family ATPase	-
ACB345_RS03520 (ACB345_03520)	rpiA	689621..690304 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44991.48 Da
• Isoelectric Point: 4.6184

>NTDB_id=1038137 ACB345_RS03500 WP_031488352.1 684357..685586(+) (clpX) [Streptococcus pyogenes strain Isolate]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIKI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1038137 ACB345_RS03500 WP_031488352.1 684357..685586(+) (clpX) [Streptococcus pyogenes strain Isolate]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGTCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTTTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTAAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.242	100	0.892
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575