Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QNH65_RS10380 Genome accession   NZ_OX352940
Coordinates   2136605..2137246 (+) Length   213 a.a.
NCBI ID   WP_024394813.1    Uniprot ID   -
Organism   Streptococcus suis isolate 861160_LM_A     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2131605..2142246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QNH65_RS10360 - 2131774..2132511 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  QNH65_RS10365 stkP 2132511..2134505 (+) 1995 WP_004194142.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  QNH65_RS10370 liaF 2134961..2135620 (+) 660 WP_223375661.1 cell wall-active antibiotics response protein LiaF -
  QNH65_RS10375 - 2135617..2136633 (+) 1017 WP_074389959.1 sensor histidine kinase -
  QNH65_RS10380 vraR 2136605..2137246 (+) 642 WP_024394813.1 response regulator transcription factor Regulator
  QNH65_RS10385 - 2137296..2138696 (+) 1401 WP_074389960.1 Cof-type HAD-IIB family hydrolase -
  QNH65_RS10390 - 2138698..2139069 (+) 372 WP_024394815.1 S1 RNA-binding domain-containing protein -
  QNH65_RS10395 cysK 2139095..2140021 (-) 927 WP_074389961.1 cysteine synthase A -
  QNH65_RS10400 - 2140111..2140743 (-) 633 WP_171840851.1 YigZ family protein -
  QNH65_RS10405 comFA/cflA 2140800..2142092 (+) 1293 WP_074389963.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23804.39 Da        Isoelectric Point: 4.8970

>NTDB_id=1037992 QNH65_RS10380 WP_024394813.1 2136605..2137246(+) (vraR) [Streptococcus suis isolate 861160_LM_A]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVIVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=1037992 QNH65_RS10380 WP_024394813.1 2136605..2137246(+) (vraR) [Streptococcus suis isolate 861160_LM_A]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGTGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTATAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACCTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCTTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

55.072

97.183

0.535
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.408

Multiple sequence alignment