Detailed information NTG1037971

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACB335_RS03990
• Genome accession: NZ_CP167022
• Coordinates: 754793..756022 (+)
• Length: 409 a.a.
• NCBI ID: WP_031488352.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 4
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 749793..761022

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB335_RS03965 (ACB335_03965)	-	750409..751686 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACB335_RS03970 (ACB335_03970)	-	751673..752848 (-)	1176	WP_031488354.1	hydroxymethylglutaryl-CoA synthase	-
ACB335_RS03975 (ACB335_03975)	-	753057..753896 (+)	840	WP_011017679.1	thymidylate synthase	-
ACB335_RS03980 (ACB335_03980)	-	753976..754473 (+)	498	WP_031488353.1	dihydrofolate reductase	-
ACB335_RS03985 (ACB335_03985)	-	754493..754663 (+)	171	WP_002990165.1	hypothetical protein	-
ACB335_RS03990 (ACB335_03990)	clpX	754793..756022 (+)	1230	WP_031488352.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACB335_RS03995 (ACB335_03995)	yihA	756032..756631 (+)	600	WP_002990160.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ACB335_RS04000 (ACB335_04000)	-	756779..757522 (+)	744	WP_002984942.1	hypothetical protein	-
ACB335_RS04005 (ACB335_04005)	-	757580..759679 (-)	2100	WP_031488351.1	AAA family ATPase	-
ACB335_RS04010 (ACB335_04010)	rpiA	760057..760740 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44991.48 Da
• Isoelectric Point: 4.6184

>NTDB_id=1037971 ACB335_RS03990 WP_031488352.1 754793..756022(+) (clpX) [Streptococcus pyogenes strain Isolate 4]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIKI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1037971 ACB335_RS03990 WP_031488352.1 754793..756022(+) (clpX) [Streptococcus pyogenes strain Isolate 4]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGTCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTTTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTAAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	89.242	100	0.892
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575