Detailed information    

insolico Bioinformatically predicted

Overview

Name   comX/sigX/comX2/sigX2   Type   Regulator
Locus tag   ACB351_RS08365 Genome accession   NZ_CP167015
Coordinates   1638728..1639279 (-) Length   183 a.a.
NCBI ID   WP_076638078.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 11     
Function   activate transcription of late competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1633728..1644279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB351_RS08340 (ACB351_08340) - 1635096..1635941 (+) 846 WP_002982833.1 mechanosensitive ion channel family protein -
  ACB351_RS08345 (ACB351_08345) - 1636006..1636566 (-) 561 WP_002988142.1 TIGR01440 family protein -
  ACB351_RS08350 (ACB351_08350) - 1636580..1637050 (-) 471 WP_002988139.1 ECF transporter S component -
  ACB351_RS08355 (ACB351_08355) - 1637040..1637804 (-) 765 WP_002988136.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  ACB351_RS08360 (ACB351_08360) truA 1637794..1638543 (-) 750 WP_002988132.1 tRNA pseudouridine(38-40) synthase TruA -
  ACB351_RS08365 (ACB351_08365) comX/sigX/comX2/sigX2 1638728..1639279 (-) 552 WP_076638078.1 competence protein ComX Regulator

Sequence

Protein


Download         Length: 183 a.a.        Molecular weight: 22228.03 Da        Isoelectric Point: 9.8369

>NTDB_id=1037604 ACB351_RS08365 WP_076638078.1 1638728..1639279(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain Isolate 11]
MSCCFFVVLFILGIVKKKRRLKMSIETRAAFEKVKPIILKLKRHYYIQLWDRDDWLQEGHIILLQLLERYPELIEEEERL
YRYFKTKFSSYLKDLLCRQESQKRQFHKLAYEEIGEVAHAIPSRGLWLDDYVAYQEVIASLENQLNSQERMQFQALIRGE
RFKGRRALLRKISPYFKEFAQQL

Nucleotide


Download         Length: 552 bp        

>NTDB_id=1037604 ACB351_RS08365 WP_076638078.1 1638728..1639279(-) (comX/sigX/comX2/sigX2) [Streptococcus pyogenes strain Isolate 11]
GTGTCCTGTTGTTTTTTTGTGGTTCTCTTTATACTAGGGATAGTTAAAAAGAAAAGGAGACTCAAAATGTCGATAGAGAC
AAGAGCAGCGTTTGAAAAAGTTAAGCCCATTATTTTGAAATTAAAGCGACACTATTATATTCAATTGTGGGATAGAGATG
ACTGGTTACAAGAAGGACATATTATCTTATTACAGTTACTAGAAAGGTACCCAGAGTTAATTGAGGAAGAAGAGCGTTTA
TATCGCTATTTTAAAACAAAATTTTCATCTTATTTGAAAGATTTATTATGCCGTCAAGAAAGTCAAAAGCGTCAGTTCCA
TAAGTTAGCATATGAAGAGATAGGGGAGGTTGCACATGCCATTCCATCGAGAGGGTTATGGCTAGACGACTATGTGGCTT
ATCAAGAGGTAATAGCTAGCTTAGAGAACCAATTAAATTCGCAAGAGCGTATGCAGTTTCAAGCACTTATCAGGGGCGAA
CGTTTCAAGGGAAGACGTGCTCTACTTAGGAAGATCAGTCCCTATTTTAAGGAATTTGCACAGCAGTTGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comX/sigX/comX2/sigX2 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes JRS4

99.454

100

0.995
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX/comX1/sigX1 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS315

98.907

100

0.989
  comX/sigX/comX2/sigX2 Streptococcus pyogenes MGAS8232

98.907

100

0.989
  comX/sigX Streptococcus infantarius subsp. infantarius ATCC BAA-102

48.667

81.967

0.399
  comX Streptococcus sobrinus strain NIDR 6715-7

45.455

84.153

0.383
  comX/sigX Streptococcus mutans UA159

43.791

83.607

0.366

Multiple sequence alignment