Detailed information NTG1036911

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: ACB348_RS01525
• Genome accession: NZ_CP167002
• Coordinates: 276896..277966 (+)
• Length: 356 a.a.
• NCBI ID: WP_009880666.1
• Uniprot ID: Q54910
• Organism: Streptococcus pyogenes strain Isolate 30
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 271896..282966

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB348_RS01510 (ACB348_01510)	amiA	272424..274394 (+)	1971	WP_136076151.1	peptide ABC transporter substrate-binding protein	Regulator
ACB348_RS01515 (ACB348_01515)	amiC	274459..275961 (+)	1503	WP_011017334.1	ABC transporter permease	Regulator
ACB348_RS01520 (ACB348_01520)	amiD	275961..276887 (+)	927	WP_111704907.1	oligopeptide ABC transporter permease OppC	Regulator
ACB348_RS01525 (ACB348_01525)	amiE	276896..277966 (+)	1071	WP_009880666.1	ABC transporter ATP-binding protein	Regulator
ACB348_RS01530 (ACB348_01530)	amiF	277959..278882 (+)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator
ACB348_RS01535 (ACB348_01535)	-	278920..279003 (-)	84	Protein_255	IS3 family transposase	-
ACB348_RS01540 (ACB348_01540)	-	279137..279447 (-)	311	Protein_256	IS3 family transposase	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39645.74 Da
• Isoelectric Point: 5.8952

>NTDB_id=1036911 ACB348_RS01525 WP_009880666.1 276896..277966(+) (amiE) [Streptococcus pyogenes strain Isolate 30]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQGLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=1036911 ACB348_RS01525 WP_009880666.1 276896..277966(+) (amiE) [Streptococcus pyogenes strain Isolate 30]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGGTTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

3D structure

• AlphaFold DB: Q54910

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.667	100	0.775
amiE	Streptococcus thermophilus LMG 18311	75.556	100	0.764
amiE	Streptococcus thermophilus LMD-9	75.556	100	0.764
oppD	Streptococcus mutans UA159	56.677	94.663	0.537