Detailed information NTG1036759

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ACB350_RS04180
• Genome accession: NZ_CP166999
• Coordinates: 782037..783266 (+)
• Length: 409 a.a.
• NCBI ID: WP_009880296.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain Isolate 34
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 777037..788266

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACB350_RS04155 (ACB350_04155)	-	777653..778930 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ACB350_RS04160 (ACB350_04160)	-	778917..780092 (-)	1176	WP_030127661.1	hydroxymethylglutaryl-CoA synthase	-
ACB350_RS04165 (ACB350_04165)	-	780301..781140 (+)	840	WP_011017679.1	thymidylate synthase	-
ACB350_RS04170 (ACB350_04170)	-	781220..781717 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ACB350_RS04175 (ACB350_04175)	-	781737..781907 (+)	171	WP_002990165.1	hypothetical protein	-
ACB350_RS04180 (ACB350_04180)	clpX	782037..783266 (+)	1230	WP_009880296.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ACB350_RS04185 (ACB350_04185)	yihA	783276..783875 (+)	600	WP_002990160.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ACB350_RS04190 (ACB350_04190)	-	784023..784766 (+)	744	WP_002984942.1	hypothetical protein	-
ACB350_RS04195 (ACB350_04195)	-	784824..786923 (-)	2100	WP_030127660.1	AAA family ATPase	-
ACB350_RS04200 (ACB350_04200)	rpiA	787301..787984 (+)	684	WP_020905094.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45020.57 Da
• Isoelectric Point: 4.6616

>NTDB_id=1036759 ACB350_RS04180 WP_009880296.1 782037..783266(+) (clpX) [Streptococcus pyogenes strain Isolate 34]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLKTSDLIRI
LTEPRNALVKQYQALLSYDGVELEFDKAALEAIATKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1036759 ACB350_RS04180 WP_009880296.1 782037..783266(+) (clpX) [Streptococcus pyogenes strain Isolate 34]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCTAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTTAAAACATCAGATTTGATTCGAATC
TTAACAGAGCCAAGGAATGCTCTTGTCAAGCAATATCAGGCCCTTCTTTCCTATGATGGGGTTGAATTAGAATTTGATAA
AGCAGCTCTTGAAGCTATCGCAACTAAAGCGATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575