Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   ACA346_RS01650 Genome accession   NZ_CP166970
Coordinates   319319..320611 (+) Length   430 a.a.
NCBI ID   WP_418127007.1    Uniprot ID   -
Organism   Streptococcus parasuis strain NX1     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 314319..325611
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA346_RS01625 (ACA346_01625) - 314977..315621 (+) 645 WP_418127004.1 response regulator -
  ACA346_RS01630 (ACA346_01630) - 315670..317070 (+) 1401 WP_418127005.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  ACA346_RS01635 (ACA346_01635) - 317072..317449 (+) 378 WP_418127006.1 S1 RNA-binding domain-containing protein -
  ACA346_RS01640 (ACA346_01640) cysK 317603..318529 (-) 927 WP_130555390.1 cysteine synthase A -
  ACA346_RS01645 (ACA346_01645) - 318630..319262 (-) 633 WP_274504533.1 YigZ family protein -
  ACA346_RS01650 (ACA346_01650) comFA/cflA 319319..320611 (+) 1293 WP_418127007.1 DEAD/DEAH box helicase Machinery gene
  ACA346_RS01655 (ACA346_01655) - 320604..321269 (+) 666 WP_274504535.1 ComF family protein -
  ACA346_RS01660 (ACA346_01660) hpf 321346..321885 (+) 540 WP_217374638.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48621.25 Da        Isoelectric Point: 9.4633

>NTDB_id=1036420 ACA346_RS01650 WP_418127007.1 319319..320611(+) (comFA/cflA) [Streptococcus parasuis strain NX1]
MNELENYHGRLFTKYQLTSEERKKAKTISSVVGKNSCFRCGTSFEEENKLPNTAYYCRACLLLGRVRTDEKLYYFPQKDF
SMNACLLWKGALTDWQQRISDGLVANVEKRQATLVHAVTGAGKTEMMYHAVASLINKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGKSDPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPILYRAADNAVKVDGVLVFLTATSTDEL
DKKVKSGKLQKLSLPRRFHGNPLVVPQKVWFSKFNTYLKKNKLVPKLRNAIQKQRETGYPLLIFVPEISKGLKFATIMEQ
IFPEETIGFVSSQTDNRLEIVEGFRNKEITILISTTILERGVTFPGVDVIVVQADHYLYTSSSLVQISGRVGRSMDRPTG
LLLFFHEGSTRSIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=1036420 ACA346_RS01650 WP_418127007.1 319319..320611(+) (comFA/cflA) [Streptococcus parasuis strain NX1]
ATGAATGAACTAGAGAATTACCATGGAAGACTTTTTACTAAATACCAATTAACGTCAGAAGAAAGAAAAAAAGCAAAAAC
AATTTCCAGTGTAGTAGGAAAGAATTCTTGTTTCCGATGCGGTACATCGTTTGAGGAAGAAAACAAGCTGCCAAATACTG
CGTATTATTGTCGGGCTTGTCTCCTTTTGGGGAGAGTTCGAACAGATGAGAAACTCTACTATTTTCCACAGAAAGATTTT
TCAATGAATGCTTGTCTTCTATGGAAGGGGGCGCTGACCGATTGGCAACAACGAATATCAGATGGACTAGTTGCGAATGT
GGAAAAACGACAAGCAACTCTTGTTCATGCTGTAACAGGTGCGGGCAAAACGGAAATGATGTACCATGCTGTTGCATCAC
TAATTAATAAAGGAGGTGCTGTATGTCTAGCCAGTCCAAGAATTGATGTTTGTATTGAACTCTACAAGCGACTACAAAAT
GATTTTTCGGTCCCAATTAGTCTGCTACATGGGAAATCAGACCCATATTTCAGAACGCCACTCGTTGTTGCGACCACTCA
TCAGTTGTTAAAGTTCTACCAGGCATTTGATTTGGTCTTGATCGATGAAGTAGATGCTTTCCCCTATGCAGACAACCCAA
TATTATATCGAGCAGCAGATAATGCAGTTAAAGTAGACGGTGTTTTAGTATTTTTAACAGCAACCTCTACGGATGAATTA
GATAAAAAAGTCAAATCAGGTAAATTGCAAAAACTCAGTCTCCCTAGGCGTTTTCATGGAAACCCGCTTGTGGTTCCGCA
AAAGGTCTGGTTTTCCAAATTCAATACATATTTGAAGAAAAATAAATTAGTTCCAAAACTCAGAAACGCCATTCAAAAGC
AAAGAGAAACAGGCTATCCATTACTTATTTTTGTACCAGAAATTTCGAAAGGATTGAAATTTGCAACCATAATGGAACAA
ATCTTTCCAGAAGAAACAATTGGTTTTGTATCGAGTCAGACAGACAATCGGCTTGAAATAGTGGAAGGATTTCGCAACAA
AGAAATTACAATTTTAATTTCTACTACAATCTTAGAGCGTGGTGTAACATTCCCAGGAGTAGATGTCATTGTTGTTCAAG
CCGATCACTACTTATACACGTCATCGAGTCTCGTGCAAATTTCAGGTCGGGTCGGAAGAAGTATGGACCGTCCGACGGGC
TTACTTCTGTTTTTTCATGAAGGAAGTACGCGGTCAATTGAAAAGGCAATTGCAGAAATCAAACAAATGAATAAGGAGGC
AGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(288-393)

Type III restriction enzyme, res subunit (ResIII)

(92-165)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

65.023

99.07

0.644
  comFA/cflA Streptococcus pneumoniae D39

65.023

99.07

0.644
  comFA/cflA Streptococcus pneumoniae R6

65.023

99.07

0.644
  comFA/cflA Streptococcus pneumoniae TIGR4

65.023

99.07

0.644
  comFA/cflA Streptococcus mitis NCTC 12261

65.023

99.07

0.644
  comFA/cflA Streptococcus mitis SK321

64.789

99.07

0.642
  comFA Lactococcus lactis subsp. cremoris KW2

50.98

94.884

0.484
  comFA Latilactobacillus sakei subsp. sakei 23K

37.063

99.767

0.37

Multiple sequence alignment