Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   ACA109_RS10140 Genome accession   NZ_CP166872
Coordinates   2001245..2001814 (-) Length   189 a.a.
NCBI ID   WP_000872876.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 24EBSta0529     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1996245..2006814
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACA109_RS10100 (ACA109_10100) - 1996718..1997326 (-) 609 WP_000020308.1 class I SAM-dependent methyltransferase -
  ACA109_RS10105 (ACA109_10105) rplL 1997501..1997869 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  ACA109_RS10110 (ACA109_10110) rplJ 1997913..1998413 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  ACA109_RS10115 (ACA109_10115) rplA 1998685..1999377 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  ACA109_RS10120 (ACA109_10120) rplK 1999585..2000007 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  ACA109_RS10125 (ACA109_10125) nusG 2000188..2000736 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  ACA109_RS10130 (ACA109_10130) secE 2000749..2000931 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  ACA109_RS10135 (ACA109_10135) rpmG 2000987..2001130 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  ACA109_RS10140 (ACA109_10140) sigH 2001245..2001814 (-) 570 WP_000872876.1 sigma-70 family RNA polymerase sigma factor Regulator
  ACA109_RS10145 (ACA109_10145) - 2001895..2002419 (-) 525 WP_000664738.1 NYN domain-containing protein -
  ACA109_RS10150 (ACA109_10150) rlmB 2002419..2003165 (-) 747 WP_000390331.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACA109_RS10155 (ACA109_10155) - 2003173..2003577 (-) 405 WP_371256665.1 Mini-ribonuclease 3 -
  ACA109_RS10160 (ACA109_10160) cysS 2003570..2004970 (-) 1401 WP_000631977.1 cysteine--tRNA ligase -
  ACA109_RS10165 (ACA109_10165) cysE 2004954..2005601 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23097.96 Da        Isoelectric Point: 9.6015

>NTDB_id=1035852 ACA109_RS10140 WP_000872876.1 2001245..2001814(-) (sigH) [Staphylococcus aureus strain 24EBSta0529]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=1035852 ACA109_RS10140 WP_000872876.1 2001245..2001814(-) (sigH) [Staphylococcus aureus strain 24EBSta0529]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGCGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

99.471

100

0.995
  sigH Staphylococcus aureus N315

98.413

100

0.984

Multiple sequence alignment