Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   AB6M99_RS06965 Genome accession   NZ_CP163513
Coordinates   1443932..1445161 (-) Length   409 a.a.
NCBI ID   WP_369350469.1    Uniprot ID   -
Organism   Streptococcus hillyeri strain S23-3001-2     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1421101..1446843 1443932..1445161 within 0


Gene organization within MGE regions


Location: 1421101..1446843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M99_RS06840 (AB6M99_06840) - 1421101..1421307 (-) 207 WP_121834754.1 YqgQ family protein -
  AB6M99_RS06845 (AB6M99_06845) - 1421408..1422139 (-) 732 WP_245962683.1 metallophosphoesterase -
  AB6M99_RS06850 (AB6M99_06850) - 1422195..1422683 (-) 489 WP_121834756.1 DNA starvation/stationary phase protection protein -
  AB6M99_RS06855 (AB6M99_06855) - 1422805..1423203 (+) 399 WP_121834757.1 prepilin peptidase -
  AB6M99_RS06860 (AB6M99_06860) - 1423266..1425014 (-) 1749 WP_369350466.1 ABC transporter ATP-binding protein -
  AB6M99_RS06865 (AB6M99_06865) - 1425004..1426746 (-) 1743 WP_121834759.1 ABC transporter ATP-binding protein -
  AB6M99_RS06870 (AB6M99_06870) - 1426899..1427387 (-) 489 WP_142925585.1 AAA family ATPase -
  AB6M99_RS06875 (AB6M99_06875) - 1427524..1428042 (-) 519 WP_369350467.1 VanZ family protein -
  AB6M99_RS06880 (AB6M99_06880) rlmN 1428042..1429139 (-) 1098 WP_121834864.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  AB6M99_RS06885 (AB6M99_06885) - 1429306..1429854 (-) 549 WP_121834762.1 YutD family protein -
  AB6M99_RS06890 (AB6M99_06890) - 1430102..1430746 (-) 645 WP_121834763.1 DUF3862 domain-containing protein -
  AB6M99_RS06900 (AB6M99_06900) - 1431255..1432415 (+) 1161 WP_121836465.1 ISAs1 family transposase -
  AB6M99_RS06910 (AB6M99_06910) rpsA 1433517..1434725 (-) 1209 WP_369350468.1 30S ribosomal protein S1 -
  AB6M99_RS06925 (AB6M99_06925) - 1435050..1435280 (-) 231 WP_121834765.1 DUF2969 domain-containing protein -
  AB6M99_RS06930 (AB6M99_06930) - 1435424..1436449 (-) 1026 WP_121834766.1 branched-chain amino acid aminotransferase -
  AB6M99_RS06935 (AB6M99_06935) parC 1436595..1439051 (-) 2457 WP_121834767.1 DNA topoisomerase IV subunit A -
  AB6M99_RS06940 (AB6M99_06940) - 1439276..1439818 (-) 543 WP_121834768.1 GNAT family N-acetyltransferase -
  AB6M99_RS06945 (AB6M99_06945) fic 1439820..1440420 (-) 601 Protein_1356 protein adenylyltransferase Fic -
  AB6M99_RS06950 (AB6M99_06950) parE 1440429..1442384 (-) 1956 WP_121834769.1 DNA topoisomerase IV subunit B -
  AB6M99_RS06955 (AB6M99_06955) - 1442542..1443234 (+) 693 WP_121834865.1 S24 family peptidase -
  AB6M99_RS06960 (AB6M99_06960) yihA 1443326..1443925 (-) 600 WP_121834770.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  AB6M99_RS06965 (AB6M99_06965) clpX 1443932..1445161 (-) 1230 WP_369350469.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  AB6M99_RS06970 (AB6M99_06970) - 1445182..1445352 (-) 171 WP_183121646.1 hypothetical protein -
  AB6M99_RS06975 (AB6M99_06975) - 1445352..1445864 (-) 513 WP_121834771.1 dihydrofolate reductase -
  AB6M99_RS06980 (AB6M99_06980) - 1445983..1446843 (-) 861 WP_121834772.1 thymidylate synthase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45288.83 Da        Isoelectric Point: 4.5461

>NTDB_id=1030298 AB6M99_RS06965 WP_369350469.1 1443932..1445161(-) (clpX) [Streptococcus hillyeri strain S23-3001-2]
MASNRKMDHKVYCSFCGKNQEEVRKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLEILNQYVVGQDR
AKRALAVAVYNHYKRVSFTESRNDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRMGEKIIGFGQNNKKIADDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTVDDLVKI
LTEPKNALVKQYKTLFSYDGVELEFDEEALQTIAAKAIERKTGARGLRSIIEETMLDIMFEIPSHEDVTGVRITKEAVEG
KAEPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1030298 AB6M99_RS06965 WP_369350469.1 1443932..1445161(-) (clpX) [Streptococcus hillyeri strain S23-3001-2]
ATGGCCTCAAACAGAAAAATGGATCACAAAGTTTATTGTTCTTTCTGTGGAAAAAATCAAGAAGAAGTTCGTAAAATTAT
CGCTGGGAATGGCGTTTTTATCTGTAACGAATGTGTCGAACTGTCTCAAGAAATTATTCGAGAAGAATTAGCAGAAGAAG
TCTTGGCTGATTTGTCAGAAGTGCCAAAACCAAAAGAACTATTAGAAATTTTAAATCAATACGTGGTCGGACAAGACAGG
GCTAAGCGTGCCCTTGCTGTGGCGGTTTACAATCATTATAAGCGTGTCAGTTTCACAGAAAGCCGTAACGATGACGATGT
TGATTTGCAAAAATCAAATATCCTTATGATTGGCCCAACAGGTTCTGGAAAGACCTTTTTAGCTCAAACATTGGCTAAAA
GTCTCAATGTACCATTTGCCATTGCCGATGCCACTTCTTTGACTGAAGCAGGTTATGTGGGTGAGGATGTTGAAAATATT
CTACTCAAACTCATCCAAGCTGCTGACTATAATATTGAACGTGCAGAGCGTGGGATTATCTACGTAGATGAGATTGATAA
AATTGCCAAAAAAGGTGAAAATGTCTCTATCACTCGAGATGTTTCTGGTGAAGGCGTGCAACAAGCCCTTCTAAAAATTA
TCGAGGGTACCGTAGCTAGCGTACCACCTCAAGGCGGACGTAAACATCCAAACCAAGAGATGATTCAAATTGATACGAAA
AACATCTTGTTCATCGTTGGTGGTGCTTTTGATGGTATTGAAGACATTGTCAAGCAACGTATGGGCGAGAAAATCATCGG
TTTTGGACAAAATAATAAAAAAATTGCCGATGATGCTTCTTACATGCAGGAAATCATCTCAGAGGACATCCAAAAATTTG
GTTTGATTCCAGAGTTCATTGGACGTTTACCAGTAGTAGCAGCTTTGGAACAATTAACTGTCGATGATTTGGTTAAAATT
TTGACTGAGCCTAAAAATGCCTTGGTAAAACAATATAAAACGCTATTTTCTTATGATGGTGTTGAATTGGAATTTGATGA
AGAAGCCTTACAAACAATTGCTGCGAAAGCTATTGAACGTAAGACAGGAGCACGTGGTCTCCGTTCTATTATTGAAGAGA
CCATGCTAGATATCATGTTTGAAATTCCAAGCCATGAAGATGTGACAGGTGTGCGTATTACGAAGGAAGCTGTCGAAGGC
AAGGCAGAACCGATTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

91.198

100

0.912
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.105

98.044

0.57

Multiple sequence alignment