Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   AB4X21_RS03040 Genome accession   NZ_CP163380
Coordinates   577121..578419 (+) Length   432 a.a.
NCBI ID   WP_369088160.1    Uniprot ID   A0AB39LCA1
Organism   Streptococcus sp. CP1998     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 572121..583419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB4X21_RS03015 (AB4X21_03015) - 572883..573515 (+) 633 WP_003004009.1 response regulator transcription factor -
  AB4X21_RS03020 (AB4X21_03020) - 573560..574960 (+) 1401 WP_003012568.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  AB4X21_RS03025 (AB4X21_03025) - 574962..575327 (+) 366 WP_003012561.1 S1 RNA-binding domain-containing protein -
  AB4X21_RS03030 (AB4X21_03030) cysK 575378..576301 (-) 924 WP_270300070.1 cysteine synthase A -
  AB4X21_RS03035 (AB4X21_03035) - 576424..577065 (-) 642 WP_003012605.1 YigZ family protein -
  AB4X21_RS03040 (AB4X21_03040) comFA/cflA 577121..578419 (+) 1299 WP_369088160.1 DEAD/DEAH box helicase Machinery gene
  AB4X21_RS03045 (AB4X21_03045) - 578416..579081 (+) 666 WP_003012565.1 ComF family protein -
  AB4X21_RS03050 (AB4X21_03050) raiA 579163..579705 (+) 543 WP_003012610.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49537.58 Da        Isoelectric Point: 9.4562

>NTDB_id=1029419 AB4X21_RS03040 WP_369088160.1 577121..578419(+) (comFA/cflA) [Streptococcus sp. CP1998]
MKIEDSYGRLLTESQMTNDLKEIAQEFPAIEKQNGRYQCFRCGSLINQKLWKLSEEVLYCRACIQLGRIRSDQKLYAIGQ
QDFEGKEVLNWKGTLTSYQQEVSEGLIHAVKAGKHALVHAVTGAGKTEMMYQVVATAIKAGKAVCIATPRIDVCIELYGR
MEEDFSCSISLLHGESEPYFRTPLVIATTHQLLKFYQAFDLLIIDEVDAFPYVDNPILYKAAQNAIKKEGNTLYLTATST
DELDKKVKKKEIIRYSLPRRFHGNPLVVPKIKWVPKIREKIEKGRIPYELLQLIKKQRQTHYPLLIFVSEIELGQQFTEN
LKKYFPKETVGFVSSQTTDRLRMVEEFRNRAITMLVSTTILERGVTFPFVDVFVLESNHKLFTKSTLVQISGRVGRSKER
PTGKLLFLSDGITREMKKAIKEIKEMNQEAGF

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=1029419 AB4X21_RS03040 WP_369088160.1 577121..578419(+) (comFA/cflA) [Streptococcus sp. CP1998]
ATGAAGATAGAAGATTCTTATGGAAGACTCTTAACGGAGAGTCAAATGACAAATGATCTAAAAGAAATTGCCCAAGAATT
TCCAGCTATAGAAAAACAGAATGGAAGGTACCAATGCTTTCGATGTGGCAGTTTGATTAATCAAAAACTGTGGAAGTTGA
GTGAAGAGGTACTGTATTGTAGAGCCTGTATCCAATTGGGAAGGATCCGGAGTGATCAAAAACTTTATGCTATTGGACAG
CAAGACTTTGAAGGAAAAGAGGTGCTAAACTGGAAAGGGACCTTGACTTCCTATCAACAAGAGGTATCTGAAGGACTTAT
CCATGCAGTTAAAGCAGGAAAACATGCCTTGGTACATGCTGTGACAGGAGCTGGAAAAACGGAAATGATGTACCAGGTTG
TAGCAACAGCGATCAAGGCAGGAAAAGCAGTCTGTATTGCTACCCCAAGAATCGATGTCTGTATAGAATTGTACGGAAGG
ATGGAGGAAGATTTTTCCTGCTCCATCTCTTTGCTTCATGGAGAATCAGAGCCCTATTTTAGAACGCCTTTAGTGATCGC
TACAACCCACCAATTGCTAAAGTTTTATCAGGCCTTTGATCTCCTTATTATAGATGAGGTAGATGCTTTTCCATATGTGG
ATAATCCAATCTTATATAAAGCAGCTCAGAATGCAATAAAAAAAGAGGGGAATACCCTATATTTGACAGCAACCTCTACA
GATGAGTTAGATAAAAAGGTCAAGAAAAAAGAAATCATTCGTTATAGTCTCCCAAGAAGATTTCATGGGAACCCACTAGT
GGTCCCTAAAATAAAATGGGTGCCGAAAATTAGAGAAAAAATAGAAAAAGGAAGAATCCCTTACGAACTATTGCAACTGA
TCAAGAAACAAAGACAGACTCACTACCCATTGTTAATCTTTGTATCTGAAATAGAATTAGGACAACAATTCACTGAGAAC
TTAAAAAAATACTTTCCCAAAGAAACAGTAGGTTTTGTATCCTCACAGACAACAGACCGTCTACGAATGGTAGAAGAGTT
TAGAAACAGAGCCATAACCATGCTAGTCTCTACAACTATTTTAGAAAGAGGAGTGACCTTTCCGTTTGTAGATGTCTTTG
TTTTAGAAAGTAATCATAAATTATTTACTAAAAGTACCCTCGTACAAATTTCAGGAAGGGTCGGTCGAAGTAAAGAAAGA
CCAACAGGTAAACTACTTTTCCTATCAGATGGCATAACACGAGAAATGAAGAAAGCGATTAAGGAAATAAAGGAAATGAA
TCAGGAGGCTGGATTTTGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-397)

Type III restriction enzyme, res subunit (ResIII)

(94-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

60.046

100

0.602
  comFA/cflA Streptococcus pneumoniae D39

60.046

100

0.602
  comFA/cflA Streptococcus pneumoniae R6

60.046

100

0.602
  comFA/cflA Streptococcus mitis SK321

59.815

100

0.6
  comFA/cflA Streptococcus pneumoniae TIGR4

59.815

100

0.6
  comFA/cflA Streptococcus mitis NCTC 12261

59.584

100

0.597
  comFA Lactococcus lactis subsp. cremoris KW2

50

92.13

0.461
  comFA Latilactobacillus sakei subsp. sakei 23K

37.644

100

0.377

Multiple sequence alignment